171048-61-6

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 6-[(3,5-dimethylphenyl)thio]-5-ethyl-
• CAS NO: 171048-61-6
• Molecular Formula: C14H16N2O2S
• Molecular Weight: 276.359
• Mol File: 171048-61-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[(3,5-dimethylphenyl)thio]-5-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[(3,5-dimethylphenyl)thio]-5-ethyl-(171048-61-6)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 6-[(3,5-dimethylphenyl)thio]-5-ethyl-(171048-61-6)

Safety Data

• Hazardous Substances Data: 171048-61-6(Hazardous Substances Data)

Upstream product

• 108-98-5 thiophenol 
• 120268-44-2 5-ethyl-6-chloro-2,4-dimethoxypyrimidine 
• 2518-72-1 5-ethyl barbituric acid 
• 1780-38-7 2,4,6-trichloro-5-ethylpyrimidine 
• 38360-81-5 3,5-Dimethylthiophenol 
• 20295-24-3 5-ethyl-6-chloro-2,4-pyrimidinedione 
• 189637-62-5 5-Ethyl-2,4-dimethoxy-6-phenylsulfanyl-pyrimidine 

Downstream Products

• 279220-45-0 3'-azido-3-[N-15-[6-(3,5-dimethylphenylthio)-5-ethyl-1-(5-oxopentyl)uracil]-4,15-diaza-3-oxopentadecanyl]-3'-deoxy-5'-O-(thexyldimethylsilyl)thymidine 
• 279220-26-7 1-(4-carboxybutyl)-6-[(3,5-dimethylphenyl)thio]-5-ethyluracil 
• 279220-25-6 5-[6-(3,5-dimethyl-phenylsulfanyl)-5-ethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-pentanoic acid methyl ester 

Relevant articles and documents

Antiviral 2,4-pyrimidinedione derivatives and process for the preparation thereof

2,4-pyrimidinedione derivatives of formula (I) having high antiviral activity against wild-type and mutant HIV-1 and low toxicity are useful for treating AIDS (I) wherein: R1is a C6-10aryl or C3-10heteroaryl group optional

Antiviral 2, 4-pyrimidinedione derivatives

Novel 2,4-pyrimidinedione compounds, and pharmaceutically acceptable salts thereof which possess good antiviral activities, and specifically represented by the following formula(I): STR1 wherein: R 1 represents an unsubstituted or substituted allyl group represented by CH 2 CH CR 5 R 6 or an unsubstituted or substituted propargyl group represented by CH 2 C CR 7 wherein R 5, R 6 and R 7 are each independently a hydrogen atom; a methyl group optionally substituted with a halogen atom, or a C 1-10 carbonyloxy, hydroxy, azido, cyano, optionally substituted amino, optionally substituted phosphonyl, optionally substituted phenyl, C 3-10 heteroaryl, C 1-3 alkoxy or benzyloxy radical; a C 2-10 alkyl or alkenyl group; a cyclopropyl group; an optionally substituted phenyl group; a C 3-10 heteroaryl group; a C 1-10 ester group; or an optionally substituted C 1-10 alkylamide group;R 2 represents a halogen atom, an optionally substituted C 1-5 alkyl, C 3-6 cycloalkyl, C 2-8 alkenyl, C 2-8 alkynyl group or a benzyl group;R 3 and R 4 represent independently a hydrogen or halogen atom, or a hydroxy, C 1-3 alkyl, fluoromethyl, C 1-3 alkoxy, amino, C 2-6 alkylester or C 2-7 alkylamide group;A represents an oxygen or sulfur atom;Z represents an oxygen or sulfur atom; a carbonyl group; an amino group; or a methylene group optionally substituted with at least one selected from the group consisting of a halogen atom, and a cyano, hydroxy, azido, amino, C 1-3 alkylamide, C 1-4 ester, and nitro groups.