171178-34-0

Basic information

• Product Name: 4-BOCAMINO-NICOTINIC ACID
• Synonyms: 4-BOCAMINO-NICOTINIC ACID;4-TERT-BUTOXYCARBONYLAMINO-NICOTINIC ACID;4-{[(tert-butoxy)carbonyl]aMino}pyridine-3-carboxylic acid
• CAS NO: 171178-34-0
• Molecular Formula: C11H14N2O4
• Molecular Weight: 238.24
• Mol File: 171178-34-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 348.358 °C at 760 mmHg
• Flash Point: 164.482 °C
• Appearance: /
• Density: 1.293 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 1.70±0.36(Predicted)
• CAS DataBase Reference: 4-BOCAMINO-NICOTINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BOCAMINO-NICOTINIC ACID(171178-34-0)
• EPA Substance Registry System: 4-BOCAMINO-NICOTINIC ACID(171178-34-0)

Safety Data

• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 36/37
• Hazardous Substances Data: 171178-34-0(Hazardous Substances Data)

Usage

General Description

4-Bocamino-nicotinic acid, also known as Boc-aminonicotinic acid, is an organic compound that belongs to the class of pyridines and derivatives. It is a derivative of nicotinic acid, which is a precursor to the coenzyme NAD. 4-Bocamino-nicotinic acid has a Boc-amino group attached to the pyridine ring, which makes it a useful intermediate in organic synthesis. 4-Bocamino-nicotinic acid is often used in the pharmaceutical industry as a building block for the synthesis of complex molecules and drugs. It has potential applications in the development of new drugs for various medical conditions, making it an important molecule in the field of medicinal chemistry.

InChI:InChI=1/C11H14N2O4/c1-11(2,3)17-10(16)13-8-4-5-12-6-7(8)9(14)15/h4-6H,1-3H3,(H,14,15)(H,12,13,16)

Upstream product

• 124-38-9 carbon dioxide 
• 98400-69-2 N-(4-pyridyl) t-butyl carbamate 
• 280115-84-6 4-tert-butoxycarbonylamino-nicotinic acid methyl ester 
• 109-72-8 n-butyllithium 
• 594-19-4 tert.-butyl lithium 
• 24424-99-5 di-tert-butyl dicarbonate 
• 7418-65-7 4-aminonicotinic acid 
• 504-24-5 4-aminopyridine 

Downstream Products

• 1664372-00-2 C₁₄H₁₁BrN₂O₂ 
• 1620955-62-5 C₁₄H₉BrN₂O 
• 1620955-63-6 C₂₀H₁₃FN₂O 
• 1620955-64-7 C₂₀H₁₂BrFN₂ 
• 1620951-98-5 1-(2-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,6-naphthyridin-4-yl)imidazolidin-2-one 
• 849777-20-4 [2-(5-chloro-2-fluoro-phenyl)-pteridin-4-ylamino]-nicotinamide hydrochloride 

Relevant articles and documents

AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF

The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions cont

AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF

The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions cont

SUBSTITUTED NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND THEIR USE IN THE TREATMENT OF HUMAN DISEASES

Inhibitors of MIF having a naphthyridine backbone are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: (Ia), (Ib), (Ic), (Id) including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein n, R, R1, R2, X, Y and Z are as defined herein. Compositions containing an inhibitor of MIF in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.