171285-18-0

Basic information

• Product Name: Acetic acid (2R,3R,4R,5R)-4,5-diacetoxy-2-[acetyl-(6-bromo-4-oxo-2-phenyl-4H-quinazolin-3-yl)-amino]-tetrahydro-pyran-3-yl ester
• CAS NO: 171285-18-0
• Molecular Weight: 616.422
• Mol File: 171285-18-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (2R,3R,4R,5R)-4,5-diacetoxy-2-[acetyl-(6-bromo-4-oxo-2-phenyl-4H-quinazolin-3-yl)-amino]-tetrahydro-pyran-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (2R,3R,4R,5R)-4,5-diacetoxy-2-[acetyl-(6-bromo-4-oxo-2-phenyl-4H-quinazolin-3-yl)-amino]-tetrahydro-pyran-3-yl ester(171285-18-0)
• EPA Substance Registry System: Acetic acid (2R,3R,4R,5R)-4,5-diacetoxy-2-[acetyl-(6-bromo-4-oxo-2-phenyl-4H-quinazolin-3-yl)-amino]-tetrahydro-pyran-3-yl ester(171285-18-0)

Safety Data

• Hazardous Substances Data: 171285-18-0(Hazardous Substances Data)

Upstream product

• 115754-65-9 6-bromo-2-phenyl-3-amino-4(3H)-quinazolinone 
• 532-20-7 D-Ribose 
• 108-24-7 acetic anhydride 
• 171482-61-4 6-Bromo-2-phenyl-3-((2R,3R,4R,5R)-3,4,5-trihydroxy-tetrahydro-pyran-2-ylamino)-3H-quinazolin-4-one 

Relevant articles and documents

REACTION OF 6-SUBSTITUTED 3-AMINO-2-PHENYL-4(3H)-QUINAZOLINONES WITH D-RIBOSE AND L-ARABINOSE

Condensation of 3-amino-2-phenyl-4(3H)-quinazolinone (Ia) and 3-amino-6-bromo-2-phenyl-4(3H)-quinazolinone (Ib) with D-ribose and L-arabinose in boiling methanol gave the corresponding N-glycosides IIa, IIIa, IIb and IIIb.Acetylation of compounds II and III, followed by Zemplen's deacetylation, afforded the N-acetyl derivatives VIa, VIb, VIIa and VIIb.According to their NMR spectra in solution, the N-ribosides exist as β-pyranosides in the 4C1(D) conformation whereas the N-arabinosides are α-pyranosides in the 4C1(L) conformation.