17131-15-6

Basic information

• Product Name: 3-(o-tolyl)propane-1,2-diol
• Synonyms: 3-(o-tolyl)propane-1,2-diol
• CAS NO: 17131-15-6
• Molecular Weight: 166.22
• Mol File: 17131-15-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(o-tolyl)propane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(o-tolyl)propane-1,2-diol(17131-15-6)
• EPA Substance Registry System: 3-(o-tolyl)propane-1,2-diol(17131-15-6)

Safety Data

• Hazardous Substances Data: 17131-15-6(Hazardous Substances Data)

Upstream product

• 16419-60-6 2-Methylphenylboronic acid 
• 1587-04-8 1-methyl-2-(2-propenyl)-benzene 
• 7399-49-7 1-methyl-2-(prop-1-en-2-yl)benzene 

Relevant articles and documents

Palladium-Catalyzed meta-C-H Olefination of Arene-Tethered Diols Directed by Well-Designed Pyrimidine-Based Group

The palladium-catalyzed meta-olefination of arene-tethered diols attached to a well-designed pyrimidine moiety is presented. Applications of the protocol are illustrated by the synthesis of various diol-based natural products, such as coumarins, phenylpropanoids, stilbenes, and chalcones. Advantages of this method are demonstrated through the easy removal of the template and a gram-scale olefination reaction. Finally, experimental verification, including 1H NMR, ESI-MS and IR, and DFT studies are undertaken to elucidate the mechanistic complexity.