17137-03-0 Usage
General Description
L-Leucine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, hydrazide, also known as Leu-Val hydrazide, is a synthetic compound with potential anticancer and chemopreventive activities. It is a selective inhibitor of the proteasome, an enzyme complex that degrades unwanted proteins in cells, and has been shown to induce apoptosis in cancer cells. L-Leucine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, hydrazide has been studied for its potential in treating various types of cancer, including breast and prostate cancer, and has shown promise in preclinical studies. It is also being investigated for its potential in combination therapies with other cancer treatments. Overall, L-Leucine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, hydrazide has shown potential in cancer research and may have future clinical applications in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 17137-03-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,3 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 17137-03:
(7*1)+(6*7)+(5*1)+(4*3)+(3*7)+(2*0)+(1*3)=90
90 % 10 = 0
So 17137-03-0 is a valid CAS Registry Number.
17137-03-0Relevant articles and documents
Synthesis of Substrates of Cyclic AMP-dependent Protein Kinase and Use of Their Protected Precursors for the Convenient Preparation of Phosphoserine Peptides
Grehn, Leif,Fransson, Bengt,Ragnarsson, Ulf
, p. 529 - 536 (2007/10/02)
The synthesis of protected hexa- to nona-peptide precursors of substrates of cycylic AMP-dependent protein kinase, based on a partial amino acid sequence from rat liver pyruvate kinase, as well as of related phosphoserine peptides has been explored.A conv