1722-07-2Relevant articles and documents
Solid-phase synthesis of diverse tetrahydro-1,4-benzodiazepine-2-ones
Bhalay, Gurdip,Blaney, Paul,Palmer, Vanessa H.,Baxter, Anthony D.
, p. 8375 - 8378 (1997)
A general method for the construction of tetrahydro-1,4-benzodiazepine- 2-ones on solid-support has been developed utilising a cleavage-conjugate addition protocol as the key step in the design. Using this novel, methodology the synthesis of a diverse one
Sunlight-Driven Forging of Amide/Ester Bonds from Three Independent Components: An Approach to Carbamates
Zhao, Yating,Huang, Binbin,Yang, Chao,Chen, Qingqing,Xia, Wujiong
, p. 5572 - 5575 (2016/11/17)
A photoredox catalytic route to carbamates enabled by visible irradiation (or simply sunlight) has been developed. This process leads to a novel approach to the construction of heterocyclic rings wherein the amide or ester motifs of carbamates were assembled from three isolated components. Large-scale experiments were realized by employing continuous flow techniques, and reuse of photocatalyst demonstrated the green and sustainable aspects of this method.
Selective mono-N-alkylation of 3-amino alcohols via chelation to 9-BBN
Bar-Haim, Galia,Kol, Moshe
, p. 3549 - 3551 (2007/10/03)
(Chemical Equation Presented) A method for selective mono-N-alkylation of amino alcohols is introduced. This method relies on formation of a stable chelate with 9-BBN, which serves in the dual roles of protecting and activating the amine group. Three prot
