17229-00-4 Usage
General Description
2-m-tolyl-thiazole-4-carboxylic acid is a chemical compound with the molecular formula C11H9NO2S. It is a thiazole derivative with a carboxylic acid group and a methyl-substituted tolyl group. 2-m-tolyl-thiazole-4-carboxylic acid has potential applications in pharmaceuticals and agrochemicals due to its structural features. Thiazole derivatives are known for their diverse biological activities, such as antimicrobial, anti-inflammatory, and antitumor properties. The presence of a carboxylic acid group makes it a potentially important molecule for the synthesis of new drugs and agrochemicals. Further research and study into the properties and potential applications of 2-m-tolyl-thiazole-4-carboxylic acid are warranted.
Check Digit Verification of cas no
The CAS Registry Mumber 17229-00-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,2,2 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17229-00:
(7*1)+(6*7)+(5*2)+(4*2)+(3*9)+(2*0)+(1*0)=94
94 % 10 = 4
So 17229-00-4 is a valid CAS Registry Number.
17229-00-4Relevant articles and documents
A catch-and-release strategy for the combinatorial synthesis of 4-acylamino-1,3-thiazoles as potential CDK5 inhibitors
Larsen, Scott D.,Stachew, Carl F.,Clare, Paula M.,Cubbage, Jerry W.,Leach, Karen L.
, p. 3491 - 3495 (2007/10/03)
Two-dimensional libraries of 4-acylamino-1,3-thiazoles 9 were prepared via Curtius rearrangement of 1,3-thiazole-4-carbonyl azides 6, trapping of the intermediate isocyanates with oxime resin, and thermal regeneration of the isocyanates from the washed resin in the presence of nucleophiles. Several compounds proved to be selective inhibitors of CDK5/p25 versus the closely homologous CDK2/cyclin A enzyme, with the best analogue (43) possessing over 100-fold selectivity.
