172362-91-3

Basic information

• Product Name: 5-Propoxy-1,3-dihydro-spiro[benzoimidazole-2,1'-cyclohexane]
• Synonyms: 5-Propoxy-1,3-dihydro-spiro[benzoimidazole-2,1'-cyclohexane]
• CAS NO: 172362-91-3
• Molecular Weight: 246.352
• Mol File: 172362-91-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Propoxy-1,3-dihydro-spiro[benzoimidazole-2,1'-cyclohexane](CAS DataBase Reference)
• NIST Chemistry Reference: 5-Propoxy-1,3-dihydro-spiro[benzoimidazole-2,1'-cyclohexane](172362-91-3)
• EPA Substance Registry System: 5-Propoxy-1,3-dihydro-spiro[benzoimidazole-2,1'-cyclohexane](172362-91-3)

Safety Data

• Hazardous Substances Data: 172362-91-3(Hazardous Substances Data)

Upstream product

• 172362-95-7 5-n-propoxy-2H-benzimidazole-2-spirocyclohexane 

Downstream Products

• 20559-55-1 methyl N-(6-propoxy-1H-benzimidazol-2-yl)carbamate 
• 56190-17-1 4-n-propoxy-o-phenylenediamine 

Relevant articles and documents

2H-benzimidazoles (isobenzimidazoles). Part 10. Synthesis of polysubstituted o-phenylenediamines and their conversion into heterocycles, particularly 2-substituted benzimidazoles with known or potential anthelminthic activity

Polysubstituted o-phenylenediamines were synthesised in moderate to high yield by reductive cleavage of the corresponding 2H-benzimidazole-2-spirocyclohexane with sodium dithionite in aqueous ethanol and converted into methyl benzimidazole-2-carbamates and 2-methylthio- and 2-trifluoro-methylbenzimidazoles with known or potential anthelminthic activity. 5-(Pyrimidin-2-ylthio)-benzimidazole and 11-(pyridin-2-ylthio)dibenzo[a,c]phenazine were synthesized too. Attempts to oxidise 1,3-dihydro-2H-4,9-diazanaphth[2,3-d]imidazole, prepared by condensation of 2,3-diaminoquinoxaline with cyclohexanone, to an analogue of the title system failed.