172455-36-6 Usage
Description
5-Chloro-4-cyano-2-nitroaniline is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its molecular structure, which includes a chlorine atom at the 5th position, a nitro group at the 2nd position, and a cyano group at the 4th position of the aniline molecule. This unique structure endows it with specific chemical properties that make it valuable in the development of pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
5-Chloro-4-cyano-2-nitroaniline is used as an intermediate in the synthesis of pharmaceutical compounds for various applications. Its chemical properties allow it to be a key component in the development of new drugs with potential therapeutic benefits.
Used in Inhibitor Synthesis:
In the pharmaceutical industry, 5-Chloro-4-cyano-2-nitroaniline is utilized as a building block for the creation of inhibitors. These inhibitors can target specific enzymes or proteins involved in various diseases, thereby providing a means to regulate or modulate their activity and potentially treat the associated conditions.
Used in Anticancer Compound Synthesis:
5-Chloro-4-cyano-2-nitroaniline is also employed in the synthesis of anticancer compounds. Its unique molecular structure allows for the development of drugs that can target cancer cells specifically, potentially leading to more effective treatments with fewer side effects compared to conventional chemotherapy.
Check Digit Verification of cas no
The CAS Registry Mumber 172455-36-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,2,4,5 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 172455-36:
(8*1)+(7*7)+(6*2)+(5*4)+(4*5)+(3*5)+(2*3)+(1*6)=136
136 % 10 = 6
So 172455-36-6 is a valid CAS Registry Number.
172455-36-6Relevant articles and documents
PHOSPHOGLYCERATE KINASE INHIBITORS
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Page/Page column 57, (2012/04/23)
Disclosed are compounds of formula (I) or pharmaceutical acceptable salts thereof, wherein R1, R2, R3 and R4 are as defined in the description. Disclosed are also the methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as phosphoglycerate kinase.
2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors
Mackman, Richard L.,Hui, Hon C.,Breitenbucher,Katz, Bradley A.,Luong, Christine,Martelli, Arnold,McGee, Danny,Radika, Kesavan,Sendzik, Martin,Spencer, Jeffrey R.,Sprengeler, Paul A.,Tario, James,Verner, Erik,Wang, Jing
, p. 2019 - 2022 (2007/10/03)
The development of potent and selective urokinase-type plasminogen activator (uPA) inhibitors based on the lead molecule 2-(2-hydroxy-3-ethoxyphenyl)-1H-benzimidazole-5-carboxamidine (3a) is described.