172479-59-3

Basic information

• Product Name: (2S)-Methyl 2-(N-tert-butoxycarbonylamino)-4-oxo-4-(2'-aminophenyl)butanoate
• Synonyms: (2S)-Methyl 2-(N-tert-butoxycarbonylamino)-4-oxo-4-(2'-aminophenyl)butanoate
• CAS NO: 172479-59-3
• Molecular Weight: 322.361
• Mol File: 172479-59-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S)-Methyl 2-(N-tert-butoxycarbonylamino)-4-oxo-4-(2'-aminophenyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-Methyl 2-(N-tert-butoxycarbonylamino)-4-oxo-4-(2'-aminophenyl)butanoate(172479-59-3)
• EPA Substance Registry System: (2S)-Methyl 2-(N-tert-butoxycarbonylamino)-4-oxo-4-(2'-aminophenyl)butanoate(172479-59-3)

Safety Data

• Hazardous Substances Data: 172479-59-3(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 201230-82-2 carbon monoxide 
• 615-43-0 2-iodophenylamine 
• 93267-04-0 N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester 

Downstream Products

• 117269-81-5 L-Kynurenine dihydrobromide 
• 2922-83-0 L-kynurenine 

Relevant articles and documents

Synthesis of l -Kynurenine and Homo- l -Kynurenine via an Aza-Fries Rearrangement

l -Kynurenine, a non-proteinogenic amino acid, is the primary metabolite of tryptophan via the kynurenine pathway. Kynurenine is involved in a variety of biological processes occurring in the human body, notably in the central nervous system. Thus, the st

Carbonylative coupling of an amino acid-derived organozine reagent with functionalized aryl iodides: Synthesis of kynurenine

The utility of the palladium(o) catalysed reaction of the serine-derived organozinc reagent 6 with functionalized aryl iodides, under a carbon monoxide atmosphere, to give protected 4-aryl-4-oxo α-amino acids 8 is illustrated by a short synthesis of L-kynurenine.