172538-83-9 Usage
Description
1(4H)-Quinolinecarboxylic acid, 4-oxo-, phenylmethyl ester, also known as Phenylmethyl 4-oxo-1,4-dihydroquinoline-3-carboxylate, is an organic compound with the chemical formula C17H13NO3. It is a derivative of quinolinecarboxylic acid and is recognized for its potential biological activities, such as anti-inflammatory and anti-cancer properties. Its phenylmethyl ester structure renders it a valuable building block for the development of novel pharmaceutical and agrochemical compounds. However, it is crucial to handle this compound with care due to its potential hazards if not used properly.
Uses
Used in Pharmaceutical Industry:
1(4H)-Quinolinecarboxylic acid, 4-oxo-, phenylmethyl ester is used as an intermediate in the synthesis of various pharmaceuticals for its potential anti-inflammatory and anti-cancer properties. Its versatile structure allows for the development of novel drug candidates that can target a range of health conditions.
Used in Agrochemical Industry:
In the agrochemical industry, 1(4H)-Quinolinecarboxylic acid, 4-oxo-, phenylmethyl ester is utilized as a key intermediate in the creation of compounds that can be applied in the development of pesticides and other agricultural chemicals, contributing to enhanced crop protection and yield.
Check Digit Verification of cas no
The CAS Registry Mumber 172538-83-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,2,5,3 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 172538-83:
(8*1)+(7*7)+(6*2)+(5*5)+(4*3)+(3*8)+(2*8)+(1*3)=149
149 % 10 = 9
So 172538-83-9 is a valid CAS Registry Number.
172538-83-9Relevant articles and documents
Cu(I)-Catalyzed Alkynylation of Quinolones
Maestro, Aitor,Lemaire, Sebastien,Harutyunyan, Syuzanna R.
, p. 1228 - 1231 (2022/02/14)
Herein we report the first alkynylation of quinolones with terminal alkynes under mild reaction conditions. The reaction is catalyzed by Cu(I) salts in the presence of a Lewis acid, which is essential for the reactivity of the system. The enantioselective version of this transformation has also been explored, and the methodology has been applied in the synthesis of the enantioenriched tetrahydroquinoline alkaloid cuspareine.
Highly Enantioselective Catalytic Addition of Grignard Reagents to N-Heterocyclic Acceptors
Guo, Yafei,Harutyunyan, Syuzanna R.
supporting information, p. 12950 - 12954 (2019/08/07)
General methods to prepare chiral N-heterocyclic molecular scaffolds are greatly sought after because of their significance in medicinal chemistry. Described here is the first general catalytic methodology to access a wide variety of chiral 2- and 4-substituted tetrahydro-quinolones, dihydro-4-pyridones, and piperidones with excellent yields and enantioselectivities, utilizing a single catalyst system.
Asymmetric synthesis of 2-aryl-2,3-dihydro-4-quinolones by rhodium-catalyzed 1,4-addition of arylzinc reagents in the presence of chlorotrimethylsilane
Shintani, Ryo,Yamagami, Takafumi,Kimura, Takahiro,Hayashi, Tamio
, p. 5317 - 5319 (2007/10/03)
(Chemical Equation Presented) The first catalytic asymmetric synthesis of 2-aryl-2,3-dihydro-4-quinolones has been developed by way of a rhodium-catalyzed 1,4-addition of arylzinc reagents to 4-quinolones. These 1,4-adducts can be obtained with high enant
