172595-31-2

Basic information

• Product Name: 8-[[5-Methoxy-1-benzyl-2-methyl-1H-indol-3-yl]-acetylamino]-octanoic acid methyl-butyl-amide
• CAS NO: 172595-31-2
• Molecular Weight: 519.728
• Mol File: 172595-31-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-[[5-Methoxy-1-benzyl-2-methyl-1H-indol-3-yl]-acetylamino]-octanoic acid methyl-butyl-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 8-[[5-Methoxy-1-benzyl-2-methyl-1H-indol-3-yl]-acetylamino]-octanoic acid methyl-butyl-amide(172595-31-2)
• EPA Substance Registry System: 8-[[5-Methoxy-1-benzyl-2-methyl-1H-indol-3-yl]-acetylamino]-octanoic acid methyl-butyl-amide(172595-31-2)

Safety Data

• Hazardous Substances Data: 172595-31-2(Hazardous Substances Data)

Upstream product

• 59283-35-1 5-methoxy-2-methyl-1-(phenylmethyl)-1H-indol-3-ylacetic acid 

Relevant articles and documents

Indole derivatives useful to treat estrogen-related neoplasms and disorders

The present invention relates to novel indole derivatives useful in down-regulating estrogen receptor expression. Also included are methods for the treatment of neoplasms or of controlling the growth of a neoplasm in a patient afflicted with a neoplastic disease, especially estrogen-dependent neoplasms such as those associated with breast, ovarian and cervical tissue. Another embodiment of the present invention is a method of prophylactically treating a patient at risk of developing a neoplastic disease state. Also provided is a method for treating autoimmune diseases. Also included are pharmaceutical compositions of the novel indole derivatives.