17277-03-1Relevant articles and documents
Solid-phase parallel synthesis of 5-amino- and 5-amido-1,2,4-thiadiazole derivatives via cyclization reactions of a carboxamidine thiourea linker
Ryu, In Ae,Park, Joo Yeon,Han, Hyea Chul,Gong, Young-Dae
experimental part, p. 999 - 1003 (2009/10/10)
A general method is described for the solid-phase parallel synthesis of 5-amino- and 5-amido-l,2,4-thiadiazoles. The sequence developed for this purpose is based on cyclization reactions of resin-bound carboxamidine thioureas promoted by p-toluenesulfonyl