172794-79-5

Basic information

• Product Name: (S)-(-)-benzyl 1-phenyl-1,2-dihydroisoquinoline-2-carboxylate
• Synonyms: (S)-(-)-benzyl 1-phenyl-1,2-dihydroisoquinoline-2-carboxylate
• CAS NO: 172794-79-5
• Molecular Weight: 341.409
• Mol File: 172794-79-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-(-)-benzyl 1-phenyl-1,2-dihydroisoquinoline-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-benzyl 1-phenyl-1,2-dihydroisoquinoline-2-carboxylate(172794-79-5)
• EPA Substance Registry System: (S)-(-)-benzyl 1-phenyl-1,2-dihydroisoquinoline-2-carboxylate(172794-79-5)

Safety Data

• Hazardous Substances Data: 172794-79-5(Hazardous Substances Data)

Upstream product

• 172794-66-0 (4S,5S)-2-(2-Bromo-benzyl)-4,5-bis-methoxymethyl-[1,3]dioxolane 
• 112396-13-1 2-(2-bromophenyl)acetaldehyde dimethyl acetal 
• 213686-67-0 (+)-N-<(αS)-2-<<(4R,5R)-4,5-bis(2-methoxypropan-2-yl)-1,3-dioxolan-2-yl>methyl>benzhydryl>-4-methylbenzenesulfonamide 
• 172794-67-1 (4R,5R)-2-(2-Bromo-benzyl)-4,5-bis-(1-methoxy-1-methyl-ethyl)-[1,3]dioxolane 
• 501-53-1 benzyl chloroformate 
• 51608-60-7 phenyl N-tosyl imine 
• 3297-72-1 1-phenylisoquinoline 
• 213686-58-9 (+)-benzyl N-<(αS)-2-<<(4R,5R)-4,5-bis(2-methoxypropan-2-yl)-1,3-dioxolan-2-yl>methyl>benzhydryl>carbamat 

Downstream Products

• 22990-19-8 (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

Asymmetric hydrogenation of quinolines and isoquinolines activated by chloroformates

(Chemical Equation Presented) Active ingredient: Optically active tetrahydroquinolines and tetrahydroisoquinolines can be obtained by the asymmetric hydrogenation of quinolines and isoquinolines with chloroformates as the activating reagent (e.g., ClCO2Bn, see scheme). The method has been applied to the asymmetric synthesis of several naturally occurring alkaloids. Bn = benzyl.

Asymmetric synthesis of 1-aryl-1,2,3,4-tetrahydroisoquinolines part 1: Addition of chiral phenylacetaldehyde acetals to acylimines

The stereoselectivity in the addition of the enantiomerically pure (2-bromophenyl)acetaldehyde acetals 3a-g to the acylimines 4a,b is investigated. Based on this reaction a novel asymmetric synthesis for the 1-phenyl-tetrahydroisoquinoline 8 is elaborated.