1728-67-2

Basic information

• Product Name: 1,4-PHENYLENEBIS-3-THIOSEMICARBAZIDE
• Synonyms: 1,4-PHENYLENE(BISTHIOSEMICARBAZIDE);1,4-PHENYLENEBIS-3-THIOSEMICARBAZIDE;1,4-PHENYLENEBIS-3-THIOSEMICARBAZIDE 96%
• CAS NO: 1728-67-2
• Molecular Formula: C₈H₁₂N₆S₂
• Molecular Weight: 256.35
• Mol File: 1728-67-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 205-206 °C
• Boiling Point: 436.8°C at 760 mmHg
• Flash Point: 218°C
• Appearance: /
• Density: 1.569g/cm³
• Vapor Pressure: 7.86E-08mmHg at 25°C
• Refractive Index: 1.872
• PKA: 10.09±0.70(Predicted)
• CAS DataBase Reference: 1,4-PHENYLENEBIS-3-THIOSEMICARBAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-PHENYLENEBIS-3-THIOSEMICARBAZIDE(1728-67-2)
• EPA Substance Registry System: 1,4-PHENYLENEBIS-3-THIOSEMICARBAZIDE(1728-67-2)

Safety Data

• Hazardous Substances Data: 1728-67-2(Hazardous Substances Data)

Usage

Appearance

White to off-white powder

Uses

a. Cross-linking agent in polymer production
b. Stabilizer in plastic manufacturing
c. Curing agent in rubber production
d. Intermediate in pharmaceutical synthesis

Antimicrobial properties

Used in antifungal and antibacterial formulations

Toxicity

Can be toxic if ingested or inhaled

Hazards

Can cause skin and eye irritation

Precaution

Handle with care due to potential health risks

InChI:InChI=1/C8H12N6S2/c9-7(15)13-11-5-1-2-6(4-3-5)12-14-8(10)16/h1-4,11-12H,(H3,9,13,15)(H3,10,14,16)

Upstream product

• 4044-65-9 1 ,4-phenylenediisothiocyanate 

Downstream Products

• 92224-66-3 N,N'-bis-[1,2,3,4]thiatriazol-5-yl-benzene-1,4-diamine 
• 96955-13-4 1,4-Bis-(isopropyliden-thio-semicarbazono)-benzol 
• 1310449-90-1 ((C₆H₅)CHNNHC(S)NH)2(C₆H₄) 
• 1192802-16-6 salicylaldehyde phenyldithiosemicarbazone 

Relevant articles and documents

1,4-Phenylenediisothiocyanate in the synthesis of bis-(thiourea, benzothiazole, quinazoline, 1,3-benzoxazine and imidazolidineiminothiones) derivatives

Interaction of 1,4-phenylenediisothiocyanate 1 with aromatic amines and o-phenylenediamine furnished the novel bisthiourea derivatives 2a-c and 7. Hydrazines or o-aminothiophenol reacted with 1 to produce bis- (thiosemicarbazide 4a,b or benzothiazole 9) d

The exocyclic functionalisation of bis(thiosemicarbazonate) complexes of zinc and copper: The synthesis of monomeric and dimeric species

This paper reports the synthesis of bimetallic zinc thiosemicarbazone complexes with rigid aromatic linkers, using either 1,3- or 1,4- benzenediamines or 1,3- or 1,4- benzenedialdehydes as the basis of the linking groups. Non-rigid aliphatic diamines and