1728-97-8

Basic information

• Product Name: 4-(4,5-diphenyl-1H-imidazol-2-yl)-N,N-dimethylaniline
• Synonyms: 4-(4,5-Diphenyl-1H-imidazol-2-yl)-N,N-dimethylaniline; Benzenamine, 4-(4,5-diphenyl-1H-imidazol-2-yl)-N,N-dimethyl-
• CAS NO: 1728-97-8
• Molecular Formula: C₂₃H₂₁N₃
• Molecular Weight: 339.4329
• Mol File: 1728-97-8.mol
• Article Data: 85

Chemical Properties

• Boiling Point: 553.5°C at 760 mmHg
• Flash Point: 288.6°C
• Density: 1.151g/cm³
• Vapor Pressure: 2.69E-12mmHg at 25°C
• Refractive Index: 1.644
• CAS DataBase Reference: 4-(4,5-diphenyl-1H-imidazol-2-yl)-N,N-dimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4,5-diphenyl-1H-imidazol-2-yl)-N,N-dimethylaniline(1728-97-8)
• EPA Substance Registry System: 4-(4,5-diphenyl-1H-imidazol-2-yl)-N,N-dimethylaniline(1728-97-8)

Safety Data

• Hazardous Substances Data: 1728-97-8(Hazardous Substances Data)

Upstream product

• 100-10-7 4-dimethylamino-benzaldehyde 
• 134-81-6 benzil 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 57-13-6 urea 
• 631-61-8 ammonium acetate 

Downstream Products

• 1728-99-0 4-(4-hydroperoxy-4,5-diphenyl-4H-imidazol-2-yl)-N,N-dimethyl-aniline 
• 255065-88-4 2‐(2‐(4‐(dimethylamino)phenyl)‐4,5‐diphenyl‐1H‐imidazol‐1‐yl)acetohydrazide 
• 6932-18-9 N,N'-Dibenzoyl-(4-dimethylamino)benzamidin 
• 39601-41-7 2-(p-dimethylaminophenyl)-4-hydroxy-4,5-diphenyl-4H-imidazole 

Relevant articles and documents

A green and simple method for the synthesis of 2,4,5-trisubstituted-1H-imidazole derivatives using acidic ionic liquid as an effective and recyclable catalyst under ultrasound

Abstract: In the current work, an acidic ionic liquid ([{(IMC)-4-OMBH}BIM][HSO4]3) has been utilized as an effective and recyclable catalyst for the synthesis of 2,4,5-trisubstituted-1H-imidazole derivatives with high yields under optimal reaction conditions and ultrasound irradiation. Important features of the new catalyst are facile synthesis, cheap reagents and successful reuse for many times. What makes the present method an effective contribution in the field of synthesis of 2,4,5-trisubstituted-1H-imidazole derivatives is the fact that it can be described as environmentally friendly, economical, short reaction time, possible recover of the catalyst, simple workup, safer and mild reaction conditions. Graphic abstract: [Figure not available: see fulltext.].

Synthesis and characterization of a new polymeric catalyst and used for the synthesis of imidazole derivatives

Cross-linked poly (4-vinylpyridine) supported TiCl4 abbreviated as [P4-VP]-Ti(IV) as a new polymeric catalyst was easily prepared and characterized by using the X-ray spectroscopy, EDS, mapping, TGA/DTG and FTIR techniques. This catalyst was used for synthesis of imidazole derivatives via one-pot three-component condensation reaction of benzil, ammonium acetate and aldehydes. This protocol offers advantages such as short reaction time, simple reaction work-up with reusability of catalyst. Graphic abstract: [Figure not available: see fulltext.].

Magnetic nanoparticle-supported sulfonic acid as a green catalyst for the one-pot synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions

In this work, magnetic nanoparticle-supported sulfonic acid (γ-Fe2O3-SO3H) is used as an efficient catalyst in the synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles in a short time (40-70 min for trisubstituted imidazoles and 30-40 min for tetrasubstituted imidazoles) and high-purity products were obtained (92-98% for trisubstituted imidazoles and 94-98% for tetrasubstituted imidazoles) in simple multicomponent reactions. The structure of these products was confirmed via FT-IR and NMR. Green and recyclable catalysts, eco-friendly and solvent-free conditions, high catalytic activity, shorter reaction time, easy recovery by an external magnet, high purity, and excellent yields are some features of these reactions.