172805-77-5

Basic information

• Product Name: 3',7-di-O-(β-hydroxyethyl)diosmetin
• Synonyms: 3',7-di-O-(β-hydroxyethyl)diosmetin
• CAS NO: 172805-77-5
• Molecular Weight: 388.374
• Mol File: 172805-77-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3',7-di-O-(β-hydroxyethyl)diosmetin(CAS DataBase Reference)
• NIST Chemistry Reference: 3',7-di-O-(β-hydroxyethyl)diosmetin(172805-77-5)
• EPA Substance Registry System: 3',7-di-O-(β-hydroxyethyl)diosmetin(172805-77-5)

Safety Data

• Hazardous Substances Data: 172805-77-5(Hazardous Substances Data)

Upstream product

• 107-07-3 2-chloro-ethanol 
• 80604-68-8 5-O-(beta-hydroxyethyl)diosmin 
• 520-27-4 diosmin 
• 520-34-3 diosmetin 

Downstream Products

• 282096-87-1 3',7-bis-O-(2-bromoethyl)diosmetin 

Relevant articles and documents

Synthesis of O-(β-hydroxyethyl) derivatives of diosmetin

Five O-(β-hydroxyethyl) derivatives (3, 4, 5, 6, 7) of diosmetin have been synthesized for the first time. Compounds 3 and 6 have been obtained by hydrolysis of 3'-O-(β-hydroxyethyl)- and 3′,5-di-O-(β-hydroxyethyl)diosmin, respectively. Compound 4 has been prepared from diosmetin, after protecting the hydroxyls at C-7 and C-3′, using ethylene oxide or ethyl chloroacetate and sodium borohydride, followed by removal of the protective groups. Compounds 5 and 7 have been prepared by the reaction of diosmetin (8) and 6 with ethylene chlorohydrin, respectively.