172890-83-4

Basic information

• Product Name: FURA PE-3 POTASSIUM SALT
• Synonyms: FURA PE-3 POTASSIUM SALT;FURA PE-3, potassium;Fura-2 LeakRes potassium salt
• CAS NO: 172890-83-4
• Molecular Formula: C37H39K4N5O17 4*
• Molecular Weight: 982.12206
• Product Categories: E-F;Stains and Dyes;Stains&Dyes, A to
• Mol File: 172890-83-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: FURA PE-3 POTASSIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: FURA PE-3 POTASSIUM SALT(172890-83-4)
• EPA Substance Registry System: FURA PE-3 POTASSIUM SALT(172890-83-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 172890-83-4(Hazardous Substances Data)

Usage

Description

FURA PE-3 POTASSIUM SALT is a fluorescent cell impermeable probe specifically designed for the detection and measurement of calcium ions (Ca2+). It is a salt form of Fura PE-3, which is known for its reduced compartmentalization and leakage compared to other calcium probes. This characteristic makes it an ideal choice for studying new fluorescent calcium indicators that are designed for cytosolic retention or measuring calcium near membranes. Fura-PE3, as a zwitterionic indicator, effectively resists the rapid leakage and compartmentalization issues that are commonly observed with fura-2 and other polycarboxylate calcium indicators.

Uses

Used in Biomedical Research:
FURA PE-3 POTASSIUM SALT is used as a research tool for studying cellular calcium signaling, which plays a crucial role in various physiological processes and cellular functions. The application reason is its ability to provide accurate and reliable measurements of intracellular calcium levels, which can help researchers better understand the underlying mechanisms of calcium-mediated processes.
Used in Dyes and Metabolites Industry:
FURA PE-3 POTASSIUM SALT is used as a component in the development of dyes and metabolites, specifically those related to calcium ion detection. The application reason is its unique properties, such as reduced compartmentalization and leakage, which make it a valuable addition to the development of new dyes and metabolites with improved performance and reliability in calcium ion detection.
Used in Drug Development:
FURA PE-3 POTASSIUM SALT can be used as a reference compound in the development of new drugs targeting calcium-related disorders. The application reason is its ability to provide insights into the behavior of calcium ions within cells, which can aid in the design and optimization of drugs that modulate calcium signaling pathways.
Used in Diagnostics:
FURA PE-3 POTASSIUM SALT can be employed in the development of diagnostic tools and assays for detecting and monitoring calcium-related conditions. The application reason is its high specificity and sensitivity in detecting calcium ions, which can help in the early detection and diagnosis of various diseases and disorders associated with abnormal calcium levels.