172935-91-0

Basic information

• Product Name: 2,6-Difluorobenzoyl hydrazine
• Synonyms: 2,6-Difluorobenzoyl hydrazine
• CAS NO: 172935-91-0
• Molecular Formula: C₇H₆F₂N₂O
• Molecular Weight: 172.13
• Mol File: 172935-91-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 2,6-Difluorobenzoyl hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Difluorobenzoyl hydrazine(172935-91-0)
• EPA Substance Registry System: 2,6-Difluorobenzoyl hydrazine(172935-91-0)

Safety Data

• Hazardous Substances Data: 172935-91-0(Hazardous Substances Data)

Usage

General Description

2,6-Difluorobenzoyl hydrazine is a chemical compound with the molecular formula C8H6F2N2O. It is a hydrazine derivative with two fluorine atoms attached to the benzoyl group. 2,6-Difluorobenzoyl hydrazine is commonly used in organic synthesis as a reagent for the preparation of various pharmaceuticals and agrochemicals. 2,6-Difluorobenzoyl hydrazine has also been studied for its potential anti-tumor and anti-inflammatory properties. It is a white to off-white crystalline solid that is slightly soluble in water and soluble in organic solvents. Due to its potential applications in medicinal chemistry, this compound is of interest to researchers in the pharmaceutical and agrochemical industries.

Upstream product

• 19064-14-3 2,6-Difluorobenzoic acid,ethyl ester 
• 13671-00-6 methyl 2,6-difluorobenzoate 
• 385-00-2 2,6-difluorobenzoic acid 

Downstream Products

• 443797-96-4 4-[[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]benzenesulfonamide 
• 929690-98-2 C₁₅H₁₀F₂N₂O₂ 
• 1310412-52-2 N-(2-butoxyethyl)-2,6-difluorobenzamide 
• 1310412-56-6 N-(2-tert-butoxyethyl)-2,6-difluorobenzamide 
• 1310412-63-5 N-[2-(tert-butyldimethylsilanyloxy)-2-phenylethyl]-2,6-difluorobenzamide 
• 1310412-44-2 1-(2,6-difluorobenzoylamino)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester 
• 1092277-13-8 5-(2,6-difluorophenyl)-1,3,4-oxadiazole-2-thione 

Relevant articles and documents

Synthesis and biological evaluation of novel resveratrol-oxadiazole hybrid heterocycles as potential antiproliferative agents

A novel class of resveratrol-oxadiazole hybrid compounds was synthesized to screen for their in vitro antiproliferative activity against three human cancer cell lines. All the compounds showed superior antiproliferative activity than the reference compound resveratrol. The most promising active compounds in this series were 1g, 2g, 1c, 2c, 2i and 1a (GI50 0.1 μM), endowed with excellent antiproliferative activity. Thus, we believe that resveratrol-oxadiazole hybrid compounds may possibly be used as a good leads for the development of new antiproliferative agents. Structures of newly synthesized compounds were confirmed by NMR and IR spectral data.

Syntheses, antifeedant activity, and QSAR analysis of new Oxa(thia)diazolyl 3(2H)-pyridazinones

Twenty-eight new oxa(thia)diazolyl 3(2H)-pyridazinone derivatives were synthesized. Some compounds showed good chronic growth activities against the armyworm, Pseudaletia separata (Walker). Their EC50 values were determined in vivo. Nineteen 2-