1733-40-0

Basic information

• Product Name: (2E)-N-phenylbut-2-enamide
• CAS NO: 1733-40-0
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.2004
• Mol File: 1733-40-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 324.1°C at 760 mmHg
• Flash Point: 189.3°C
• Density: 1.08g/cm³
• Vapor Pressure: 0.000251mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: (2E)-N-phenylbut-2-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-N-phenylbut-2-enamide(1733-40-0)
• EPA Substance Registry System: (2E)-N-phenylbut-2-enamide(1733-40-0)

Safety Data

• Hazardous Substances Data: 1733-40-0(Hazardous Substances Data)

Usage

Description

(2E)-N-phenylbut-2-enamide, also known as N-phenyl-2-buteneamide, is a chemical compound with the molecular formula C12H13NO. It is an amide derivative of phenylbutene, featuring a phenyl group attached to the C-N bond of the enamide double bond. (2E)-N-phenylbut-2-enamide is characterized by its unique structure and reactivity, which makes it a valuable building block in organic chemistry.

Uses

Used in Organic Chemistry Research:
(2E)-N-phenylbut-2-enamide is used as a starting material for the synthesis of other organic compounds. Its chemical properties and reactivity make it a valuable building block for the production of pharmaceuticals, agrochemicals, and other fine chemicals.
Used in Pharmaceutical Industry:
(2E)-N-phenylbut-2-enamide is used as an intermediate in the synthesis of pharmaceuticals. Its unique structure and reactivity allow for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
(2E)-N-phenylbut-2-enamide is used as a precursor in the production of agrochemicals. Its chemical properties make it suitable for the development of new pesticides and other agricultural chemicals.
Used in Fine Chemicals Production:
(2E)-N-phenylbut-2-enamide is used as a building block for the production of fine chemicals. Its versatility in chemical reactions allows for the creation of a wide range of specialty chemicals for various applications.
Used in Biological Activity Research:
(2E)-N-phenylbut-2-enamide has been studied for its potential biological activities, including antimicrobial and anti-inflammatory properties. Its unique structure and reactivity make it a promising candidate for further research and development in the field of bioactive compounds.

Upstream product

• 503-64-0 (Z)-but-2-enoic acid 
• 3724-65-0 2-butenoic acid 
• 108-24-7 acetic anhydride 
• 625-35-4 trans-chrotonyl chloride 
• 62-53-3 aniline 
• 71-43-2 benzene 
• 107-93-7 (E)-but-2-enoic acid 
• 10487-71-5 crotonyl chloride 
• 13140-15-3 N-phenyl-3-butenamide 
• 142-04-1 aniline hydrochloride 
• 21988-86-3 sodium crotonate 
• 95-14-7 1,2,3-Benzotriazole 
• 98-95-3 nitrobenzene 

Downstream Products

• 4734-38-7 3-piperidino-butyric acid anilide 
• 24652-02-6 3-morpholino-butyric acid anilide 
• 93501-09-8 α,β-Dibromohydrocrotonanilide 
• 861588-03-6 (+/-)-1-phenylcarbamoyl-propane-2-sulfonic acid ; (+/-)-β-sulfo-butyric acid anilide 
• 1129-50-6 N-phenylbutyramide 
• 74973-28-7 3,4,4-Trimethyl-pentanoic acid phenylamide 
• 74973-27-6 N,3-diphenylbutanamide 
• 102-01-2 N-phenylacetoacetamide 
• 1092514-22-1 2,5-dihydro-2-methyl-4-(methylamino)-5-oxo-N-phenylfuran-3-carboxamide 
• 1298077-88-9 3-(methylamino)-1-phenyl-1H-pyrrole-2,5-dione 
• 1332483-23-4 N-phenyl-13-apo-β-caroten-13-amide 
• 1332483-28-9 N-phenyl-14'-apo-β-caroten-14'-amide 

Relevant articles and documents

INTERMOLEKULARE CC-VERKNUEPFUNG VON AZANICKELACYCLOPENTANONEN, α,ω-DISAEUREAMIDE AUS ALKENEN UND PHENYLISOCYANAT

The reaction mode of the nickela five-membered ring complexes, prepared from phenyl isocyanate and the alkenes ethene, propene and styrene at (Lig)Ni0 systems, with oxidizing reagents such as FeCl3 and iodine are reported.Depending on the ligan

Amide bond formation in aqueous solution: Direct coupling of metal carboxylate salts with ammonium salts at room temperature

Herein, we report a green, expeditious, and practically simple protocol for direct coupling of carboxylate salts and ammonium salts under ACN/H2O conditions at room temperature without the addition of tertiary amine bases. The water-soluble coupling reagent EDC·HCl is a key component in the reaction. The reaction runs smoothly with unsubstituted/substituted ammonium salts and provides a clean product without column chromatography. Our reaction tolerates both carboxylate (which are unstable in other forms) and amine salts (which are unstable/volatile when present in free form). We believe that the reported method could be used as an alternative and suitable method at the laboratory and industrial scales. This journal is

Catalytic base-controlled regiodivergent heteronucleophilic hydrofunctionalization of β,γ-unsaturated amides

A general catalytic base-controlled regiodivergent nucleophilic hydrofunctionalization of both terminal and internal β,γ-unsaturated amides has been reported. The atom-economical addition of various S/P-based nucleophiles was also exclusively chemoselective. More than 60 branched or linear hetero-substituted aliphatic amides were synthesized from common starting materials under transition-metal-free conditions. Preliminary mechanistic studies are consistent with our proposed divergent catalytic cycles.