173310-52-6

Basic information

• Product Name: 2-methyl-4-oxo-5-(phenylthio)pentanal
• Synonyms: 2-methyl-4-oxo-5-(phenylthio)pentanal
• CAS NO: 173310-52-6
• Molecular Weight: 222.308
• Mol File: 173310-52-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-4-oxo-5-(phenylthio)pentanal(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-4-oxo-5-(phenylthio)pentanal(173310-52-6)
• EPA Substance Registry System: 2-methyl-4-oxo-5-(phenylthio)pentanal(173310-52-6)

Safety Data

• Hazardous Substances Data: 173310-52-6(Hazardous Substances Data)

Upstream product

• 13307-75-0 (phenylthio)methyllithium 
• 82884-40-0 methyl 2-methyl-3-<(trimethylsilyl)oxy>-1-cyclopropanecarboxylate 
• 64190-48-3 dihydro-4-methyl-2(3H)-furanone 
• 173310-48-0 2-methyl-4-oxo-5-(phenylthio)pentanol 

Relevant articles and documents

and Annulation Reactions of α-(Phenylthio) Dicarbonyl Electrophiles with Bis(trimethylsilyl) Enol Ethers: Synthesis of Highly Functionalized Medium Ring Cycles

The and annulations of bis(trimethylsilyl) enol ethers with 1,4- and 1,5-dicarbonyl electrophiles bearing α-phenylthio substituents leads to the formation of bicyclic and ethers with good regiochemical and stereochemical control.Subsequent oxidation of the phenylthio moiety followed by reduction with SmI2 constitutes a high-yielding and regioselective process for cleavage of the bridging ether linkage.The overal strategy provides a synthetic pathway for the synthesis of highly functionalized medium ring carbocycles.