173416-01-8

Basic information

• Product Name: (1-FURAN-2-YL-BUT-3-ENYL)-(4-METHOXY-PHENYL)-AMINE
• Synonyms: (1-FURAN-2-YL-BUT-3-ENYL)-(4-METHOXY-PHENYL)-AMINE
• CAS NO: 173416-01-8
• Molecular Formula: C₁₅H₁₇NO₂
• Molecular Weight: 243.3
• Mol File: 173416-01-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 343.1°Cat760mmHg
• Flash Point: 161.3°C
• Appearance: /
• Density: 1.097g/cm³
• Vapor Pressure: 7.22E-05mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: (1-FURAN-2-YL-BUT-3-ENYL)-(4-METHOXY-PHENYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (1-FURAN-2-YL-BUT-3-ENYL)-(4-METHOXY-PHENYL)-AMINE(173416-01-8)
• EPA Substance Registry System: (1-FURAN-2-YL-BUT-3-ENYL)-(4-METHOXY-PHENYL)-AMINE(173416-01-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 173416-01-8(Hazardous Substances Data)

Usage

General Description

(1-Furan-2-yl-but-3-enyl)-(4-methoxy-phenyl)-amine, also known as 2-amino-1-((furan-2-yl)ethyl)-5-(4-methoxyphenyl)pent-4-en-1-one, is a chemical compound with the molecular formula C18H19NO2. It belongs to the class of aromatic amines and contains a furan ring, a butenyl group, and a methoxyphenyl group. (1-FURAN-2-YL-BUT-3-ENYL)-(4-METHOXY-PHENYL)-AMINE is commonly used in organic synthesis and pharmaceutical research for its potential biological activities. It may have applications in the development of novel drugs and pharmacological agents due to its structural and functional properties. Further research and studies may be required to fully understand the potential uses and effects of this chemical compound.

InChI:InChI=1/C15H17NO2/c1-3-5-14(15-6-4-11-18-15)16-12-7-9-13(17-2)10-8-12/h3-4,6-11,14,16H,1,5H2,2H3

Upstream product

• 1749-14-0 N-furfurylidene-p-anisidine 
• 24850-33-7 allyltributylstanane 
• 100239-11-0 (E)-N-2-furylidene-4-methoxyaniline 
• 762-72-1 allyl-trimethyl-silane 
• 106-95-6 allyl bromide 
• 107-18-6 allyl alcohol 
• 98-01-1 furfural 
• 104-94-9 4-methoxy-aniline 
• 383-67-5 allyl trifluoroacetate 
• 54655-41-3 B-allyl-1,3,2-dioxaborinane 

Relevant articles and documents

Asymmetric Petasis Borono-Mannich Allylation Reactions Catalyzed by Chiral Biphenols

Chiral biphenols catalyze the asymmetric Petasis borono-Mannich allylation of aldehydes and amines through the use of a bench-stable allyldioxaborolane. The reaction proceeds via a two-step, one-pot process and requires 2–8 mole % of 3,3′-Ph2-BINOL as the optimal catalyst. Under microwave heating the reaction affords chiral homoallylic amines in excellent yields (up to 99 %) and high enantioselectivies (er up to 99:1). The catalytic reaction is a true multicomponent condensation reaction whereas both the aldehyde and the amine can possess a wide range of structural and electronic properties. Use of crotyldioxaborolane in the reaction results in stereodivergent products with anti- and syn-diastereomers both in good diastereoselectivities and enantioselectivities from the corresponding E- and Z-borolane stereoisomers.

Palladium-catalyzed, one-pot, three-component synthesis of homoallylic amines from aldehydes, anisidine, and allyl trifluoroacetate

(Chemical Equation Presented) An allylation reaction that generates homoallylic amines using allyl trifluoroacetate as a nucleophilic allylmetal precursor is reported. A palladium complex catalyzes two transformations in one pot: formation of allylsilane

New synthetic approach to substituted isoindolo[2,1-a]quinoline carboxylic acids via intramolecular Diels-Alder reaction of 4-(N-furyl-2)-4- arylaminobutenes-1 with maleic anhydride

Acylation of substituted 4-(furyl-2)-4-arylaminobut-1-enes with maleic anhydride provided 2-allyl-6-carboxy-4-oxo-3-aza-10-oxatricyclo[5.2.1.0 1,5]dec-8-enes in high yield under mild reaction conditions. The Diels-Alder adducts are formed via an initial amide formation followed by a stereoselective intramolecular [4+2] exo-cycloaddition reaction. Treatment of the tricyclic compounds with phosphoric acid at high temperatures (70-120°C) promoted cyclic ether opening, intramolecular cyclization and aromatization to give the corresponding tetracyclic compounds, 5,6,6a,11-tetrahydro-10- carboxyisoindolo[2,1-a]quinolines, in moderate yields. The influence of the acid and the reaction temperature on the cyclization reactions are also discussed.