173458-96-3

Basic information

• Product Name: 1H-Pyrrole-3-carboxylic acid, 2-amino-5-(2-methoxyphenyl)-, ethyl ester
• CAS NO: 173458-96-3
• Molecular Formula: C14H16N2O3
• Molecular Weight: 260.293
• Mol File: 173458-96-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-carboxylic acid, 2-amino-5-(2-methoxyphenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carboxylic acid, 2-amino-5-(2-methoxyphenyl)-, ethyl ester(173458-96-3)
• EPA Substance Registry System: 1H-Pyrrole-3-carboxylic acid, 2-amino-5-(2-methoxyphenyl)-, ethyl ester(173458-96-3)

Safety Data

• Hazardous Substances Data: 173458-96-3(Hazardous Substances Data)

Upstream product

• 31949-21-0 bromomethyl 2-methoxyphenyl ketone 
• 50551-10-5 ethyl amidinoacetate 
• 2318-25-4 ethyl 3-ethoxy-3-iminopropanoate hydrochloride 
• 141-52-6 sodium ethanolate 
• 57508-48-2 carbethoxyacetamidine hydrochloride 

Downstream Products

• 873192-80-4 2-[3-(2-chloro-ethyl)-ureido]-5-(2-methoxy-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester 

Relevant articles and documents

3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high-affinity and selective α1- adrenoceptor ligands

The discovery of a new series of selective and high-affinity α1-adrenoceptor (α1-AR) ligands, characterized by a 1H-pyrrolo[2,3-d]-pyrimidine-2,4(3H,7H)-dione system, is described in this paper. Some synthesized compounds, including 20, 22, and 30, displayed affinity in the nanomolar range for α1-ARs and substantial selectivity with respect to 5-HT1A and dopaminergic D1 and D 2 receptors. Functional assays, performed on selected derivatives, showed antagonistic properties.