173468-90-1Relevant articles and documents
Novel bridgehead nitrogen heterocycles: Facile synthesis and antimicrobial activity of 2,3-diaryl-3,3a,6,7,8,9-hexahydro-2H-pyrazolothiazolodiazepines
Mohan, Jag,Singh, Virender,Malik, Nirmal
, p. 1105 - 1106 (2007/10/03)
A facile synthesis of 2,3-diaryl-3,3a,6,7,8,9-hexahydro-2H-pyrazolothiazolodiazepines (3) has been achieved in a single-step by treating 2-arylidene-5,6,7,8-tetrahydrothiazolodiazepin-3(2H)-ones (2) with hydrazines.Compounds 2 is turn have been obtained in a single-step by condensing 4,5,6,7-tetrahydro-1H-1,3-diazepine-2-thiol (1) with ethyl chloroacetate and aldehydes in the presence of pyridine and piperidine.Compounds 3 represent a novel and hitherto unknown heterocyclic system.The antibacterial and antifungal activities of some of the compounds of this system have also been evaluated.