1735-87-1

Basic information

• Product Name: 2,2-BIS(TRIFLUOROMETHYL)PROPIONYL FLUORIDE
• Synonyms: 2,2-BIS(TRIFLUOROMETHYL)PROPIONYL FLUORIDE;2,2-Bis(trfluoromethyl)propanol Fluoride;2,2-Bis(trifluoromethyl)propanoyl fluoride;2,2-Bis(trifluoromethyl)propionyl fluoride, 2-Methyl-3,3,3-trifluoro-2-(trifluoromethyl)propanoyl fluoride
• CAS NO: 1735-87-1
• Molecular Formula: C5H3F7O
• Molecular Weight: 212.07
• Mol File: 1735-87-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 47-49°C
• Flash Point: 7.9°C
• Appearance: /
• Density: 1,473 g/cm3
• Refractive Index: 1.293
• CAS DataBase Reference: 2,2-BIS(TRIFLUOROMETHYL)PROPIONYL FLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-BIS(TRIFLUOROMETHYL)PROPIONYL FLUORIDE(1735-87-1)
• EPA Substance Registry System: 2,2-BIS(TRIFLUOROMETHYL)PROPIONYL FLUORIDE(1735-87-1)

Safety Data

• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3265
• Hazardous Substances Data: 1735-87-1(Hazardous Substances Data)

Usage

General Description

2,2-Bis(trifluoromethyl)propionyl fluoride, also known as bis(trifluoromethyl)acetyl fluoride, is a chemical compound with the molecular formula C5H3F6O2. It is a colorless, volatile liquid with a sharp, pungent odor. It is primarily used as a reagent in organic synthesis, particularly in the formation of trifluoromethyl ketones. It is also used as a fluorinating agent in the pharmaceutical and agrochemical industries. Due to its highly reactive nature and potential for hazardous reactions, it should be handled and stored with caution in a controlled laboratory environment.

Upstream product

• 360-53-2 1,3,3,3-tetrafluoro-1-methoxy-2-trifluoromethyl-propene 
• 382-22-9 3,3,3-trifluoro-2-trifluoromethyl-propionyl fluoride 
• 74-88-4 methyl iodide 

Downstream Products

• 1736-33-0 α-Methyl-hexafluoroisobuttersaeure-anilid 
• 382-09-2 1,1,1,3,3,3-hexafluoro-2-methyl-propane 
• 2253-00-1 1,1,3,3,3-pentafluoro-2-methyl-1-propene 

Relevant articles and documents

Exchange reactions of organotin and organosilicon compounds with vinylic fluorine

Compounds carrying reactive fluorine atoms, such as methylphosphonis difluoride and perfluoroisobutene, undergo facile exchange with organosilanes and stannanes.Reactions with protic nucleophiles also yield similar products.To account for the products formed and observed reactivity differences, appropriate mechanisms are proposed.The reactions described herein have considerable synthetic utility.

Synthesis of 1-aroyl(1-arylsulfonyl)-4-bis(trifluoromethyl)alkyl semicarbazides as potential physiologically active compounds

1,1-Bis(trifluoromethyl)alkyl isocyanates obtained from perfluoroisobutene (PFIB) react with aroyl(arylsulfonyl)hydrazines. Twenty eight prospective biologically active polyfluorinated 1,4-substituted semicarbazides were synthesized. The structure of each

CONVERSION OF METHOXYPERFLUOROISOBUTENE TO α-METHYLHEXAFLUOROISOBUTYRIC ACID FLUORIDE BY A PHASE TRANSFER CATALYST

Methoxyperfluoroisobutene was converted to α-methylhexafluoroisobutyric acid fluoride by a catalytic amount of phase transfer catalyst in quantitative yield.