17357-32-3

Basic information

• Product Name: 2-BROMO-1-(5-BROMOFURAN-2-YL)-ETHANONE
• Synonyms: 2-BROMO-1-(5-BROMOFURAN-2-YL)-ETHANONE
• CAS NO: 17357-32-3
• Molecular Formula: C₆H₄Br₂O₂
• Molecular Weight: 267.9
• Mol File: 17357-32-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-BROMO-1-(5-BROMOFURAN-2-YL)-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-1-(5-BROMOFURAN-2-YL)-ETHANONE(17357-32-3)
• EPA Substance Registry System: 2-BROMO-1-(5-BROMOFURAN-2-YL)-ETHANONE(17357-32-3)

Safety Data

• Hazardous Substances Data: 17357-32-3(Hazardous Substances Data)

Upstream product

• 3199-50-6 1-(5-bromofuran-2-yl)ethanone 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 26726-16-9 5-bromofuran-2-carbonyl chloride 

Downstream Products

• 585-70-6 5-bromo-furan-2-carboxylic acid 
• 731822-26-7 2-[5-(4-cyanophenyl)furan-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile 
• 731822-42-7 2-[5-(4-cyanophenyl)furan-2-yl]-8-methylimidazo[1,2-a]pyridine-6-carbonitrile 
• 731822-88-1 N-hydroxy-2-{5-[4-(N-hydroxyamidino)phenyl]furan-2-yl}imidazo[1,2-a]pyridine-6-carboxamidine 
• 731822-44-9 N-hydroxy-2-{5-[4-(N-hydroxyamidino)phenyl]furan-2-yl}-8-methylimidazo[1,2-a]pyridine-6-carboxamidine 
• 53757-29-2 2-methyl-4-(5'-nitro-2'-furyl)thiazole 
• 657405-39-5 C₁₂H₈Cl₂O₂ 
• 1245794-44-8 1-methyl-2-phenyl-5-(5'-bromo-2'-furyl)imidazole 

Relevant articles and documents

Synthesis and properties of 1-methyl-2-phenyl-5-(2-furyl)- and 1-methyl-2-phenyl-5-(2-thienyl)imidazoles

2-Phenyl-5-(2-furyl)- and 2-phenyl-5-(2-thienyl)imidazoles were synthesized by condensation of 2-furoylmethyl and 2-thenoylmethyl acetates with benzaldehyde under the conditions of Weidenhagen reaction. The products were converted to N-methyl derivatives in the KOH-acetone system. The electrophilic substitution reactions of the products (acylation, bromination, nitration, sulfonation, hydroxymethylation) were studied.

Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1, 2-a]pyridines as antiprotozoal agents

2-[5-(4-Amidinophenyl)-furan-2-yl]-5,6,7,8-tetrahydro-imidazo [1,2-a]pyridine-6-carboxamidine acetate salt (7) was synthesized from 2-[5-(4-cyanophenyl)-furan-2-yl]-imidazo[1,2-a]pyridine-6-carbonitrile (4a), through the bis-O-acetoxyamidoxime followed by

Synthesis and evaluation of a novel series of pyrrolizine derivatives as dual cyclooxygenase-1 and 5-lipoxygenase inhibitors

The aim of our study was to investigate structure activity relationship following the replacement of the 6-phenyl substituent at the 6,7-diaryl-2,3-dihydropyrrolizine template by various heteroaromatic residues. In this context we developed a new, efficient, and highly sensitive test method for the screening of dual cyclooxygenase-1 (COX-1) and 5-lipoxygenase (5-LOX) inhibitors. We used human platelets as a source of COX-1 and human PMNLs as a source of 5-LOX. Both cell types were isolated from the same volume of blood. PGE2 and LTB4 respectively were determined by highly selective and sensitive ELISA kits, using monoclonal antibodies. For a single determination at most 0.5 mL whole blood is needed.