17359-83-0Relevant articles and documents
An approach to pyrazoline-fused chlorins by dipolar [3 + 2]-cycloaddition of iminonitriles to Meso-Tetrakis(pentafluorophenyl)porphyrin: Synthesis of new PDT photosensitizers
Wyrebek, Przemyslaw,Ostrowski, Stanislaw
, p. 1167 - 1174,8 (2020/09/16)
Meso-Tetrakis(pentafluorophenyl)porphyrin reacts at higher temperature with unstable iminonitriles (RC≡N+-N--Ar), affording pyrazoline-fused chlorins, according to dipolar [3 + 2]-cycloaddition pathway. The respective iminonitriles were in situ generated from the corresponding functionalized α-halogenohydrazine derivatives by 1,3-elimination of HX in the presence of base (NEt3, DABCO). This method allows synthesis of very attractive moieties which may be of potential use as sensitizers in photodynamic therapy (PDT).
Halogenation of Substituted Hydrazones. A Facile Route for the Synthesis of Some New Hydrazidoyl Halides
Tewari, Ram S.,Parihar, Padma
, p. 418 - 420 (2007/10/02)
A wide variety of new alkyl, aryl, acyl and ethoxycarbonyl derivatives of hydrazidoyl halides have been synthesized by the electrophilic attack of the halogen atom on the corresponding hydrazone chain.The structural assignments of the products are based o