173678-25-6

Basic information

• Product Name: 6-Acetyl-2-(1,1-dimethylethyl)-7-methylpyrazolo<1,5-a>pyrimidine
• Synonyms: 6-Acetyl-2-(1,1-dimethylethyl)-7-methylpyrazolo<1,5-a>pyrimidine
• CAS NO: 173678-25-6
• Molecular Weight: 231.297
• Mol File: 173678-25-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-Acetyl-2-(1,1-dimethylethyl)-7-methylpyrazolo<1,5-a>pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Acetyl-2-(1,1-dimethylethyl)-7-methylpyrazolo<1,5-a>pyrimidine(173678-25-6)
• EPA Substance Registry System: 6-Acetyl-2-(1,1-dimethylethyl)-7-methylpyrazolo<1,5-a>pyrimidine(173678-25-6)

Safety Data

• Hazardous Substances Data: 173678-25-6(Hazardous Substances Data)

Upstream product

• 33884-41-2 ethoxylideneacetylacetone 
• 82560-12-1 3-tert-butyl-1H-pyrazole-5-amine 

Relevant articles and documents

New 2,3-substituted 4,7-dihydro-6-(1'H-pyrazol-3'-yl)pyrazolo[1,5-a]pyrimidin-7-ones and related compounds: Synthesis and benzodiazepine receptor binding study

The reaction between two series of 7-dimethylaminovinyl pyrazolo[1,5-a]pyrimidines 4(a-r) 7a, 7d, 7f, 7(h-j) and hydrazine in acetic acid is investigated. The structure of 4,7-dihydro-6-(1'H-pyrazol-3'-yl)pyrazolo[1,5-a]pyrimidin-7-ones 5(a-r) and 7-methyl-6-(1'H-pyrazol-3'-yl)pyrazolo[1,5a]pyrimidines 8a, 8d, 8f, 8(h-j) are attributed to the isolated products and the pathway of this reaction is suggested. The in vitro benzodiazepine receptor (BzR) affinity of the title compounds are determined by testing their ability to displace 3H-flunitrazepam from its specific binding in bovine brain membranes. The IC50 and GABA (γ-aminobutyric acid) ratio values give valuable indications about affinity and behavioural profile of these new BzR ligands. Included in this investigation are indicated several structure affinity relationships of the title compounds.