173680-72-3

Basic information

• Product Name: (S)-1-phenyl-1-octyn-3-ol
• Synonyms: (S)-1-phenyl-1-octyn-3-ol
• CAS NO: 173680-72-3
• Molecular Weight: 202.296
• Mol File: 173680-72-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (S)-1-phenyl-1-octyn-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-phenyl-1-octyn-3-ol(173680-72-3)
• EPA Substance Registry System: (S)-1-phenyl-1-octyn-3-ol(173680-72-3)

Safety Data

• Hazardous Substances Data: 173680-72-3(Hazardous Substances Data)

Upstream product

• 27975-79-7 1-phenyloct-1-yn-3-ol 
• 66-25-1 hexanal 
• 536-74-3 phenylacetylene 
• 14371-10-9 (E)-3-phenylpropenal 
• 591-50-4 iodobenzene 
• 32556-71-1 1-octyn-3-ol 
• 2579-22-8 Phenylpropargyl aldehyde 
• 14402-93-8 dipentylzinc 

Relevant articles and documents

New Enantioselective Syntheses of Acetylenic Alcohols Using Functionalized Diorganozincs

Two new enantioselective preparations of polyfunctional propargylic alcohols (82 to >96 percent ee) have been developed.They were obtained by using the addition of functionalized dialkylzincs to acetylenic aldehydes in the presence of a 1:1 mixture of Ti(

Utilization of whole cell mediated deracemization in a chemoenzymatic synthesis of enantiomerically enriched polycyclic chromeno[4,3-b] pyrrolidines

Various aryl and alkyl substituted optically pure propargyl alcohols were obtained with excellent ee (up to >99%) and isolated yields (up to 87%) by deracemization using whole cells of Candida parapsilosis ATCC 7330. The whole cells show substrate specificity towards alkyl substituted propargyl alcohols and a switch in the enantioselectivity has been observed from 'R' to 'S' upon increasing the chain length. For the first time, enantiopure (R)-4-(3-hydroxybut-1-ynyl)benzonitrile, (R)-4-(biphenyl-4-yl)but-3-yn-2-ol, (S)-ethyl 3-hydroxy-5-phenylpent-4-ynoate and (S)-4-phenylbut-3-yne-1,2-diol were obtained using this strategy. Optically pure propargyl alcohol thus obtained was used as a chiral starting material in the synthesis of enantiomerically enriched poly-substituted pyrrolidines and a pyrrole derivative successfully demonstrating a chemoenzymatic route. This journal is

Enantiospecific synthesis of 1,3-disubstituted allenes by palladium-catalyzed coupling of propargylic compounds with arylboronic acids

An enantiospecific coupling of propargylic esters and carbonates with arylboronic acids has been developed using a palladium catalyst. Optically active 1,3-disubstituted allenes were synthesized with high enantiomeric excesses by carrying out the reaction