173950-08-8

Basic information

• Product Name: (S)-1-(allyloxy)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-ol
• Synonyms: (S)-1-(allyloxy)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-ol
• CAS NO: 173950-08-8
• Molecular Weight: 434.532
• Mol File: 173950-08-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (S)-1-(allyloxy)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(allyloxy)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-ol(173950-08-8)
• EPA Substance Registry System: (S)-1-(allyloxy)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-ol(173950-08-8)

Safety Data

• Hazardous Substances Data: 173950-08-8(Hazardous Substances Data)

Upstream product

• 56083-15-9 (S)-4-((allyloxy)methyl)-2,2-dimethyl-1,3-dioxolane 
• 123-34-2 (R)-3-allyloxypropane-1,2-diol 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 173950-09-9 Trifluoro-methanesulfonic acid (S)-3-allyloxy-2-benzyloxy-propyl ester 
• 106401-57-4 1-O-allyl-2-O-benzyl-sn-glycerol 

Relevant articles and documents

MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE

The present disclosure provides for compounds of Formula (I) wherein A2, A3, A4, A6, A7, A8, A15, RA, R5, R9, R10A, R10B, R11, R12, R13, R14, R16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of Formula (I).

MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE

The present disclosure provides for compounds of formula (I), wherein A2, A3, A4, A6, A7, A8, A15, RA, R5, R9, R10A, R10B, R11, R12, R13, R14, R16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of formula (I).