174087-66-2

Basic information

• Product Name: 1-Phenyl-5-((E)-2-thiophen-2-yl-vinyl)-1H-pyrazole-3-carboxylic acid hydrazide
• CAS NO: 174087-66-2
• Molecular Weight: 310.379
• Mol File: 174087-66-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Phenyl-5-((E)-2-thiophen-2-yl-vinyl)-1H-pyrazole-3-carboxylic acid hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-5-((E)-2-thiophen-2-yl-vinyl)-1H-pyrazole-3-carboxylic acid hydrazide(174087-66-2)
• EPA Substance Registry System: 1-Phenyl-5-((E)-2-thiophen-2-yl-vinyl)-1H-pyrazole-3-carboxylic acid hydrazide(174087-66-2)

Safety Data

• Hazardous Substances Data: 174087-66-2(Hazardous Substances Data)

Upstream product

• 174087-61-7 1-phenyl-3-ethoxycarbonyl-5-[(2'-thienyl)ethen-1'-yl]pyrazole 
• 874-83-9 2-thenylideneacetone 

Downstream Products

• 174087-90-2 1-Phenyl-5-((E)-2-thiophen-2-yl-vinyl)-1H-pyrazole-3-carboxylic acid [1-phenyl-meth-(Z)-ylidene]-hydrazide 
• 174087-95-7 5-[1-Phenyl-5-((E)-2-thiophen-2-yl-vinyl)-1H-pyrazol-3-yl]-3H-[1,3,4]oxadiazole-2-thione 
• 174087-91-3 1-Phenyl-5-((E)-2-thiophen-2-yl-vinyl)-1H-pyrazole-3-carboxylic acid [1-thiophen-2-yl-meth-(Z)-ylidene]-hydrazide 

Relevant articles and documents

Synthesis of heterocyclic compounds from δ-unsaturated 1,3-diketo-esters

Diketo-esters (1) have been synthesised and converted to the corresponding pyrazole (2), isoxazole (8) and 4-pyrone (10) derivatives. Fusion of 2 with hydrazine hydrate give the corresponding acid hydrazides (3). Reaction of 3 with the appropriate isothiocyanate yield the disubstituted thiosemicarbazides (4) which are cyclized into thiotriazoles (5), thiadiazoles (6) and oxadiazoles (7). Condensation of 3 with aromatic aldehydes yield the corresponding arylidenes (11) which are cyclized to dihydro-oxadiazole (12) and oxadiazole (13) derivatives. The Mannich bases (15) have also been prepared from the oxadiazole-2-thione (14).