17417-10-6Relevant articles and documents
Vicarious nucleophilic substitution of hydrogen in 2,4-dinitroanilines and cyanonitroanilines
Makosza,Voskresensky,Bialecki,Kwast
, p. 1969 - 1977 (2007/10/03)
Orientation of the VNS reaction in nitroaniline derivatives is mostly governed by the conjugation between the nitro groups and the amino group, which could be also deprotonated under the reaction conditions.
REACTION OF 2,4-DISUBSTITUTED CHLOROBENZENES WITH 3-ALKYLAMINO- AND 3-DIALKYLAMINOPROPIONITRILES
Plakidin, Val. L.,Vostrova, V. N.
, p. 295 - 303 (2007/10/02)
The reaction of 2,4-disubstituted chlorobenzenes with 3-dialkylaminopropionitriles at 65-170 deg C leads to the formation of 2,4-disubstituted N,N-dialkylanilines, and the reaction with 3-alkylaminopropionitriles at 20-130 deg C leads to the formation of 2,4-disubstituted N-alkyl-N-β-cyanoethylanilines.In addition, in the latter case at high temperature (130 deg C) the cyanoethyl group is removed from the substituted N-alkyl-N-β-cyanoethylaniline with the formation of the 2,4-disubstituted N-alkylaniline.