174355-17-0

Basic information

• Product Name: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one
• Synonyms: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one
• CAS NO: 174355-17-0
• Molecular Weight: 287.434
• Mol File: 174355-17-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one(174355-17-0)
• EPA Substance Registry System: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one(174355-17-0)

Safety Data

• Hazardous Substances Data: 174355-17-0(Hazardous Substances Data)

Upstream product

• 61049-69-2 3-O-benzylmaltol 
• 118-71-8 Maltol 
• 61160-18-7 3-benzyloxy-2-methyl-1H-pyridin-4-one 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Downstream Products

• 174355-18-1 Acetic acid (2R,3R,4R,5R)-4,5-diacetoxy-2-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-tetrahydro-pyran-3-yl ester 
• 87597-94-2 1-β-D-ribofuranosyl-3-hydroxy-2-methyl-4-pyridone 
• 654054-85-0 3-Hydroxy-1-((2R,5S)-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-methyl-1H-pyridin-4-one 
• 654054-85-0 3-Hydroxy-1-((2S,5S)-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-methyl-1H-pyridin-4-one 
• 654054-82-7 (1'S,4'S)-1-[5'-tert-butyldiphenylsilyl-2',3'-dideoxy-α-D-ribofuranosyl]-2-methyl-3-benzyloxy-4-pyridinone 
• 654054-81-6 (1'R,4'S)-1-[5'-tert-butyldiphenylsilyl-2',3'-dideoxy-β-D-ribofuranosyl]-2-methyl-3-benzyloxy-4-pyridinone 
• 174355-19-2 C₃₉H₃₃NO₉ 

Relevant articles and documents

Synthesis and antiviral evaluation of 3-hydroxy-2-methylpyridin-4-one dideoxynucleoside derivatives

We describe the synthesis and the antiviral evaluation of novel α and β dideoxynucleoside derivatives in which the base has been replaced by a 3-hydroxy-2-methylpyridin-4-one. The syntheses were successfully achieved by the use of the standard Vorbrueggen coupling conditions. Moderate activity of these compounds were found on herpes simplex virus (HSV) type 1 and type 2.

Efficient synthesis of N-[(2-hydroxyethoxy) methyl]-2-alkyl-3-hydroxy-4-pyridinone by a modified Hilbert-Johnson reaction

Ethyleneglycol derivatives of 2-methyl (and ethyl)-3-hydroxy-4-pyridinone were synthesized by a modified Hilbert-Johnson reaction. The synthesis proceeds by reaction of O-protected 2-alkyl-3-hydroxy-4-pyridinone with hexamethyldisilazane in the presence o