174402-43-8 Usage
Molecular weight
430.24 g/mol
Chemical structure
1H-Pyrrole-2,5-dione with a bromine atom at the 3-position, a methyl group at the 1-position, and a 6-(phenylmethoxy)-1H-indol-3-yl group at the 4-position.
Appearance
Yellow crystalline solid
Solubility
Slightly soluble in water, soluble in organic solvents such as methanol and dimethyl sulfoxide (DMSO)
+ Anti-inflammatory
Tryptanthrin has been shown to inhibit the expression of inflammatory mediators and cytokines.
+ Antioxidant
Tryptanthrin has demonstrated antioxidant properties, which may help protect cells from oxidative stress and damage.
+ Anticancer
Tryptanthrin has been shown to induce cell cycle arrest and apoptosis in cancer cells, suggesting its potential as a cancer therapeutic agent.
+ Antibacterial
Tryptanthrin has demonstrated antibacterial activities against certain strains of bacteria.
+ Antiviral
Tryptanthrin has shown antiviral activities against certain viruses.
+ Melting point
195-198°C
+ UV-visible absorption
Tryptanthrin absorbs UV light in the visible range, with a maximum absorption at 415 nm.
+ Fluorescence
Tryptanthrin exhibits strong blue fluorescence under UV light, with an emission wavelength of 445 nm.
Check Digit Verification of cas no
The CAS Registry Mumber 174402-43-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,4,0 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 174402-43:
(8*1)+(7*7)+(6*4)+(5*4)+(4*0)+(3*2)+(2*4)+(1*3)=118
118 % 10 = 8
So 174402-43-8 is a valid CAS Registry Number.
174402-43-8Relevant articles and documents
Novel substituted [1,4] benzodioxino[2,3-e] isoindole derivatives, method for preparing and pharmaceutical compositions containing same
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Page/Page column 12, (2010/10/19)
Compounds of formula (I): wherein: A is as defined in the description, Y represents a group selected from an oxygen atom and a methylene group, R2 represents a hydrogen atom and in that case: R3 represents a group selected from a hydrogen atom and the groups linear or branched (C1-C6)alkyl, aryl, aryl-(C1-C6)alkyl (in which the alkyl moiety is linear or branched) and SO2CF3, or R2 and R3 form a bond, R1 represents a group selected from a hydrogen atom and the groups linear or branched (C1-C6)alkyl, aryl and aryl-(C1-C6)alkyl (in which the alkyl moiety is linear or branched) or a linear or branched (C1-C6)alkylene chain, Z1 and Z2 each represent a hydrogen atom or Z1 and Z2, together with the carbon atoms carrying them, form a phenyl group. Medicaments.
Practical synthesis of indolopyrrolocarbazoles
Ohkubo, Mitsuru,Nishimura, Teruyuki,Jona, Hideki,Honma, Teruki,Morishima, Hajime
, p. 8099 - 8112 (2007/10/03)
A practical method for the synthesis of an indolo[2,3-a]pyrrolo[3,4- c]carbazole ring system is described. The method involves two key processes: a coupling reaction between indole and substituted methylmaleimide portions using lithium hexamethyldisilazide (LiHMDS) as a base, and the oxidative cyclization of bisindolylmaleimide with palladium (II) chloride. We applied this method to the synthesis of arcyriaflavin B (5), C (6) and D (7).
