174417-54-0

Basic information

• Product Name: 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID
• Synonyms: 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID
• CAS NO: 174417-54-0
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.08
• EINECS: 604-604-1
• Mol File: 174417-54-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 353.194°C at 760 mmHg
• Flash Point: 167.406°C
• Appearance: /
• Density: 1.547g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID(174417-54-0)
• EPA Substance Registry System: 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID(174417-54-0)

Safety Data

• Hazardous Substances Data: 174417-54-0(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-methoxy-3-methylbenzoic acid is a chemical compound with the molecular formula C9H9BrO3. It is a white to off-white crystalline solid that is commonly used in the synthesis of pharmaceuticals and agrochemicals. 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID is notable for its bromo and methoxy functional groups, which contribute to its reactivity and biological activity. 2-Bromo-5-methoxy-3-methylbenzoic acid is often employed as an intermediate in organic synthesis and can be utilized in the production of various drugs and other organic compounds. Its structure and properties make it a valuable building block in the field of medicinal chemistry and drug discovery.

InChI:InChI=1/C9H9BrO3/c1-5-3-6(13-2)4-7(8(5)10)9(11)12/h3-4H,1-2H3,(H,11,12)

Upstream product

• 6267-34-1 2-bromo-5-methoxy-1,3-dimethyl-benzene 
• 110451-90-6 (2-bromo-5-methoxy-3-methylphenyl)methanol 
• 874-63-5 3,5-dimethylmethoxybenzene 
• 164513-49-9 2-bromo-1-(bromomethyl)-5-methoxy-3-methylbenzene 
• 108-68-9 3,5-Dimethylphenol 
• 1336-21-6 ammonium hydroxide 

Downstream Products

• 94742-92-4 methyl 2-bromo-5-methoxy-3-methylbenzoate 
• 207287-39-6 (S)-2-(2-Bromo-5-methoxy-3-methyl-phenyl)-4-isopropyl-4,5-dihydro-oxazole 
• 174417-56-2 1-Allyl-1-(2-bromo-5-methoxy-3-methyl-phenyl)-5,7-dimethoxy-1,3-dihydro-isobenzofuran 
• 174417-55-1 Acetic acid 2-(2-bromo-5-methoxy-3-methyl-benzoyl)-3,5-dimethoxy-benzyl ester 
• 174417-57-3 3-[1-(2-Bromo-5-methoxy-3-methyl-phenyl)-5,7-dimethoxy-3-oxo-1,3-dihydro-isobenzofuran-1-yl]-propionic acid 
• 631910-81-1 (2-bromo-5-methoxy-3-methyl-phenyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R1, R2, R3, R4 and R7 are defined in the specification, Z is SO or SO2, and Ar is an aromatic or heteroaromatic group as defined herein.

NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R1, R2, R3, R4 and R7 are defined in the specification, Z is SO or SO2, and Ar is an aromatic or heteroaromatic group as defined herein.

SYNTHESIS OF OPTICALLY ACTIVE O,O,O-TRIMETHYLKORUPENSAMINES A AND B

Hydrolysis of benzofuran derivative (10) with concomitant aromatisation produced the biaryl system (11).Subsequent Sharpless asymmetric epoxidation of the cinnamyl alcohol (13) gave atropisomers (14) and (15) conveniently separated by chromatography.Indep