17451-62-6 Usage
Description
N-Methyl-L-histidine Hydrochloride (N-ME-HIS-OH HCL) is a salt analog of N-Methyl-L-histidine, a naturally occurring amino acid derivative found in various proteins. It is characterized by the presence of a methyl group attached to the histidine molecule and is commonly used in scientific research and pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
N-ME-HIS-OH HCL is used as a reagent for the preparation of acylsulfanylhistidines, which serve as precursors to sulfanylhistidines and disulfides. These compounds have potential applications in the development of new drugs and therapeutic agents.
Used in Research Applications:
N-ME-HIS-OH HCL is utilized in the study of betaine and ovothiol biosynthesis, which are important processes in the metabolism and regulation of various biological systems. This research can contribute to a better understanding of these processes and their potential applications in medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 17451-62-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,4,5 and 1 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 17451-62:
(7*1)+(6*7)+(5*4)+(4*5)+(3*1)+(2*6)+(1*2)=106
106 % 10 = 6
So 17451-62-6 is a valid CAS Registry Number.
17451-62-6Relevant articles and documents
Benzoazepine-Fused Isoindolines via Intramolecular (3 + 2)-Cycloadditions of Azomethine Ylides with Dinitroarenes
Wales, Steven M.,Rivinoja, Daniel J.,Gardiner, Michael G.,Bird, Melissa J.,Meyer, Adam G.,Ryan, John H.,Hyland, Christopher J. T.
supporting information, p. 4703 - 4708 (2019/06/27)
Aminobenzaldehydes bearing a pendant 3,5-dinitrophenyl group react thermally with N-substituted α-amino acids to form unprecedented benzoazepine-fused isoindolines. The reaction proceeds via a dearomatization/rearomatization sequence involving an intramolecular (3 + 2)-cycloaddition between the in situ formed azomethine ylide and the dinitroarene. Various glycine derivatives are tolerated as well as branched substrates based on cyclic, α-mono-, and α,α-disubstituted amino acids, giving single diastereomers in many cases. The method is scalable and gives products with a nitro group ready for further manipulation.