174533-54-1

Basic information

• Product Name: 4-Amino-3-[2-(4-chloro-phenyl)-acetylamino]-benzoic acid methyl ester
• CAS NO: 174533-54-1
• Molecular Weight: 318.76
• Mol File: 174533-54-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Amino-3-[2-(4-chloro-phenyl)-acetylamino]-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-[2-(4-chloro-phenyl)-acetylamino]-benzoic acid methyl ester(174533-54-1)
• EPA Substance Registry System: 4-Amino-3-[2-(4-chloro-phenyl)-acetylamino]-benzoic acid methyl ester(174533-54-1)

Safety Data

• Hazardous Substances Data: 174533-54-1(Hazardous Substances Data)

Upstream product

• 36692-49-6 Methyl 3,4-diaminobenzoate 
• 25026-34-0 4-chlorophenacetyl chloride 

Relevant articles and documents

Synthesis of some new benzimidazole-5(6)-carboxylic acids

The title compounds, 1,2-dialkyl-benzimidazole-5(6)-carboxylic acids 34-45 were prepared at four steps; 1) preparation of mono amide derivatives 1-11 by the reaction of methyl 3,4-diaminobenzoate and substituted phenyl or phenoxyacetic acid chlorides; 2) preparation of the methyl benzimidazolecarboxylates 12-22, with zinc chloride and dry hydrogen chloride gas; 3) alkaline hydrolysis of the esters 23-33; and 4) substitution of the imidazole ring with benzyl or p-fluorobenzyl bromide, in alkali medium. 2-Aryl-benzimidazole-5(6)-carboxylic acids 50-53 were prepared via the oxidative condensation of 3,4-diaminobenzoic acid and aromatic aldehydes with cupric ion.