174538-64-8

Basic information

• Product Name: {4-[5-(3-Benzoyl-thioureido)-4-carbamoyl-[1,2,3]triazol-1-ylmethoxy]-butyl}-phosphonic acid diethyl ester
• Synonyms: {4-[5-(3-Benzoyl-thioureido)-4-carbamoyl-[1,2,3]triazol-1-ylmethoxy]-butyl}-phosphonic acid diethyl ester
• CAS NO: 174538-64-8
• Molecular Weight: 512.527
• Mol File: 174538-64-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {4-[5-(3-Benzoyl-thioureido)-4-carbamoyl-[1,2,3]triazol-1-ylmethoxy]-butyl}-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {4-[5-(3-Benzoyl-thioureido)-4-carbamoyl-[1,2,3]triazol-1-ylmethoxy]-butyl}-phosphonic acid diethyl ester(174538-64-8)
• EPA Substance Registry System: {4-[5-(3-Benzoyl-thioureido)-4-carbamoyl-[1,2,3]triazol-1-ylmethoxy]-butyl}-phosphonic acid diethyl ester(174538-64-8)

Safety Data

• Hazardous Substances Data: 174538-64-8(Hazardous Substances Data)

Upstream product

• 174538-04-6 diethyl <4-(azidomethoxy)butyl>phosphonate 
• 174538-01-3 diethyl <4-(chloromethoxy)butyl>phosphonate 
• 15916-48-0 diethyl but-3-en-1-ylphosphonate 
• 63075-64-9 diethyl (4-hydroxybutyl)phosphonate 

Downstream Products

• 174538-67-1 {4-[5-(3-Benzoyl-2-methyl-isothioureido)-4-carbamoyl-[1,2,3]triazol-1-ylmethoxy]-butyl}-phosphonic acid diethyl ester 

Relevant articles and documents

Guanine, pyrazolo[3,4-d]pyrimidine, and triazolo[4,5-d]pyrimidine (8-azaguanine) phosphonate acyclic derivatives as inhibitors of purine nucleoside phosphorylase

Phosphonate acyclic derivatives of guanines, pyrazolo[3,4-d]pyrimidines, and triazolo[4,5-d]-pyrimidines (8-azaguanines) are inhibitors of the enzyme purine nucleoside phosphorylase (PNPase) with K′1 values ranging from 0.05 to 1.6 μM. These compounds are enzymatically stable congeners of the potent PNPase inhibitor acyclovir diphosphate (53).