174560-84-0Relevant articles and documents
Concise synthesis of (S)-N-BOC-2-hydroxymethylmorpholine and (S)-N-BOC-morpholine-2-carboxylic acid
Henegar, Kevin E.
, p. 3662 - 3665 (2008)
(Chemical Equation Presented) An operationally simple synthesis of N-BOC-2-hydroxymethylmorpholine (1) and N-BOC-morpholine-2-carboxylic acid (2) from epichlorohydrin has been developed. No chromatography is required in the processing, which allows high p
Efficient one-pot synthesis of enantiomerically pure 2-(hydroxymethyl)- morpholines
Breuning, Matthias,Winnacker, Malte,Steiner, Melanie
, p. 2100 - 2106 (2008/02/06)
An efficient and convenient one-pot procedure for the synthesis of enantiomerically pure 2-(hydroxymethyl)morpholines with a widely variable substitution pattern was developed. Addition of chiral β-amino alcohols to (S)- or (R)-epichlorohydrin in the pres