174603-54-4

Basic information

• Product Name: Propanedioic acid, [(2-bromo-4-fluorophenyl)methyl]-, diethyl ester
• CAS NO: 174603-54-4
• Molecular Formula: C14H16BrFO4
• Molecular Weight: 347.181
• Mol File: 174603-54-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [(2-bromo-4-fluorophenyl)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [(2-bromo-4-fluorophenyl)methyl]-, diethyl ester(174603-54-4)
• EPA Substance Registry System: Propanedioic acid, [(2-bromo-4-fluorophenyl)methyl]-, diethyl ester(174603-54-4)

Safety Data

• Hazardous Substances Data: 174603-54-4(Hazardous Substances Data)

Upstream product

• 1422-53-3 2-bromo-4-fluorotoluene 
• 61150-57-0 2-bromo-4-fluorobenzyl bromide 
• 105-53-3 diethyl malonate 

Downstream Products

• 174603-56-6 4-bromo-6-fluoro-indan-1-one 
• 174603-55-5 3-(2-bromo-4-fluoro-phenyl)-propionic acid 

Relevant articles and documents

Indanylidenes. 2. Design and synthesis of (E)-2-(4-chloro-6-fluoro-1-indanylidene)-N-methylacetamide, a potent antiinflammatory and analgesic agent without centrally acting muscle relaxant activity

Extension of the structure-activity relationship studies that led to the discovery of the nonsedating potent muscle relaxant, antiinflammatory, and analgesic agent (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 1, has given rise to (E)-2-(4-chloro-6-fluoro

3-ARYL-5-SUBSTITUTED-ISOQUINOLIN-1-ONE COMPOUNDS AND THEIR THERAPEUTIC USE

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 3-aryl-5-substituted- 2/-/-isoquinolin-1-one compounds that, inter alia, inhibit PARP (e.g., PARP1, TNKS1, TNKS2, e