174607-36-4

Basic information

• Product Name: 6-Trifluoromethylpyridazin-3(2H)-one
• Synonyms: 6-Trifluoromethylpyridazin-3(2H)-one;6-(trifluoroMethyl)-2,3-dihydropyridazin-3-one;6-(Trifluoromethyl)pyridazin-3(2h)-on
• CAS NO: 174607-36-4
• Molecular Formula: C₅H₃F₃N₂O
• Molecular Weight: 164.0853296
• Mol File: 174607-36-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 80-81 °C
• Appearance: /
• Density: 1.55±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 10.05±0.40(Predicted)
• CAS DataBase Reference: 6-Trifluoromethylpyridazin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Trifluoromethylpyridazin-3(2H)-one(174607-36-4)
• EPA Substance Registry System: 6-Trifluoromethylpyridazin-3(2H)-one(174607-36-4)

Safety Data

• Hazardous Substances Data: 174607-36-4(Hazardous Substances Data)

Usage

General Description

6-Trifluoromethylpyridazin-3(2H)-one, also known as trifluoromethylpyridazinone, is a chemical compound with the molecular formula C5H2F3N3O. It is a heterocyclic compound containing a pyridazinone ring and a trifluoromethyl group. 6-Trifluoromethylpyridazin-3(2H)-one has potential applications in pharmaceutical and agrochemical industries due to its unique properties and reactivity. It can be used as a building block in the synthesis of various biologically active molecules. The trifluoromethyl group also imparts significant changes in the physicochemical and biological properties of the resulting compounds, making this chemical of interest for drug discovery and development. Additionally, research has been conducted to explore its potential as a herbicide or fungicide. In summary, 6-Trifluoromethylpyridazin-3(2H)-one is a versatile compound with diverse applications in the field of chemistry and life sciences.

Upstream product

• 628332-15-0 6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one 
• 258506-68-2 3-chloro-6-(trifluormethyl)pyridazine 

Downstream Products

• 258506-68-2 3-chloro-6-(trifluormethyl)pyridazine 
• 1192040-30-4 tert-butyl cyclopentyl(4-{[6-oxo-3-(trifluoromethyl)pyridazin-1(6H)-yl]methyl}phenyl)acetate 
• 1073525-71-9 3,4-dibromo-6-trifluoromethyl-pyridazine 

Relevant articles and documents

OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF

The present application relates to novel carboxylic acid derivatives having an oxo-substituted azaheterocyclic partial structure, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

4-ALKOXYPYRIDAZINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS

The present invention relates to (1-benzyl-piperidin-4-yl) - (4-alkoxy-pyridazin-3-yl) - amines of formula (I) that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.

1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY

A compound represented by the formula (1) wherein ring A is a ring optionally having 1 to 3 substituents; ring B is a 1,2-azole ring which may further have 1 to 3 substituents; Xa, Xb and Xc are the same or different and each is a bond, - O -, - S - and the like; Ya is a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; Yb and Yc are the same or different and each is a bond or a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; ring C is a monocyclic aromatic ring which may further have 1 to 3 substituents; and R represents -OR4 (R4 is hydrogen atom or optionally substituted hydrocarbon group) and the like, or a salt thereof or a prodrug thereof is useful as an agent for the prophylaxis or treatment of diabetes and the like.