174623-07-5

Basic information

• Product Name: 4-(5-Formylthiophen-2-yl)benzoic acid
• Synonyms: 4-(5-Formylthien-2-yl)benzoic acid;5-(4-Carboxyphenyl)thiophene-2-carboxaldehyde;4-(5-Formyl-2-thienyl)benzoic acid 97%
• CAS NO: 174623-07-5
• Molecular Formula: C₁₂H₈O₃S
• Molecular Weight: 232.26
• Product Categories: Building Blocks;C10 to C20+;Chemical Synthesis;Heterocyclic Building Blocks;New Products for Chemical Synthesis;Thiophenes
• Mol File: 174623-07-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 284-290℃
• Appearance: /
• CAS DataBase Reference: 4-(5-Formylthiophen-2-yl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-Formylthiophen-2-yl)benzoic acid(174623-07-5)
• EPA Substance Registry System: 4-(5-Formylthiophen-2-yl)benzoic acid(174623-07-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 174623-07-5(Hazardous Substances Data)

Usage

Uses

4-(5-Formyl-2-thienyl)benzoic Acid is a useful intermediate in organic synthesis.

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 150-13-0 4-amino-benzoic acid 
• 639816-37-8 4-(5-formyl-2-thiophenyl)benzoic acid methyl ester 
• 4701-17-1 5-bromo-2-thiophencarboxaldehyde 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 

Downstream Products

• 618913-75-0 2-(4-carboxyphenyl)-5-(6-cyanobenzothiazol-2-yl)thiophene 
• 618913-79-4 2-(4-chlorocarbonylphenyl)-5-(6-cyanobenzothiazol-2-yl)thiophene 
• 174623-12-2 2-(5-p-Chlorocarbonylphenyl-2-thienyl)-benzothiazole 
• 1313398-23-0 4-(5-formylthiophen-2-yl)-N-methylbenzamide 
• 1313397-43-1 N-methyl-4-(5-((5-oxo-2-thioxoimidazolidin-4-ylidene)-methyl)thiophen-2-yl)benzamide 
• 1313398-24-1 4-(5-formylthiophen-2-yl)-N,N-dimethylbenzamide 
• 1313397-44-2 N,N-dimethyl-4-(5-((5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)thiophen-2-yl)benzamide 
• 1313398-33-2 4-(5-formylthiophen-2-yl)-N-(2-morpholinoethyl)benzamide 
• 1313397-50-0 N-(2-morpholinoethyl)-4-(5-((5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)thiophen-2-yl)benzamide 
• 1313398-29-6 4-(5-formylthiophen-2-yl)-N-(3-morpholinopropyl)benzamide 
• 1313397-48-6 N-(3-morpholinopropyl)-4-(5-((5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)thiophen-2-yl)benzamide 
• 1313398-27-4 4-(5-formylthiophen-2-yl)-N-(2-hydroxyethyl)benzamide 
• 1313397-47-5 N-(2-hydroxyethyl)-4-(5-((5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)thiophen-2-yl)benzamide 
• 1313398-31-0 4-(5-formylthiophen-2-yl)-N-(3-hydroxypropyl)benzamide 

Relevant articles and documents

HETEROCYCLIC INTEGRIN AGONISTS

The present invention provides polycyclic oxothioxoimidazolidines, dioxoimidazolines, oxothioxooxazolidines, dioxooxazolidines, and related compounds, which are useful as integrin agonists. Methods for the treatment of integrin-mediated diseases such as cancer are also described.

Synthesis of new cyano-substituted bis-benzothiazolyl arylfurans and arylthiophenes

The new compounds 2-[4-(6-cyanobenzothiazol-2-yl)phenyl]-5-(6-cyano- benzothiazol-2-yl)furan (6a) and 2-[4-(6-Cyanobenzothiazol-2-yl)phenyl]-5-(6- cyano-benzothiazol-2-yl)thiophene (6b) were synthesized by multi-step reactions from the corresponding 2-fur