174759-01-4Relevant articles and documents
Reaction of 6-Substituted 3-Amino-2-aryl-4(3H)-quinazolinones with D-Glucose and D-Galactose
Abdo, M. Anwar.,Abdel-Megeed, M. Farghaly,Saleh, M. Atia.,El-Hiti, G. Abdel-Rahman
, p. 583 - 590 (2007/10/02)
The reaction of 6-substituted 3-amino-2-aryl-4(3H)-quinazolinones (1-5) with D-Glucose and D-Galactose in boiling methanol in the presence of acetic acid as a catalyst yielded a mixture of α- and β-anomers of 6-substituted 2-aryl-3--amino-4-(3H)-quinazolinones.The N-glycopyranoside derivatives 6-12 were acetylated with acetic anhydride/pyridine to give the corresponding acetates 13-19.Deacetylation of 13, 14, 18, 19 gave 6-substituted 2-aryl-3--amino-4(3H)-quinazolinones (20-23) as sterically hindered exo- andendo-isomers.Key words: N-glycopyranoside, cerbohydicles