174774-65-3

Basic information

• Product Name: 5-(benzyloxycarbonylamidino)-2-benzofurancarboxylic acid
• Synonyms: 5-(benzyloxycarbonylamidino)-2-benzofurancarboxylic acid
• CAS NO: 174774-65-3
• Molecular Weight: 338.32
• Mol File: 174774-65-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(benzyloxycarbonylamidino)-2-benzofurancarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzyloxycarbonylamidino)-2-benzofurancarboxylic acid(174774-65-3)
• EPA Substance Registry System: 5-(benzyloxycarbonylamidino)-2-benzofurancarboxylic acid(174774-65-3)

Safety Data

• Hazardous Substances Data: 174774-65-3(Hazardous Substances Data)

Upstream product

• 144-55-8 sodium hydrogencarbonate 
• 84102-76-1 ethyl 5-cyanobenzo[d]furan-2-carboxylate 
• 199609-33-1 5-Carbamimidoyl-benzofuran-2-carboxylic acid methyl ester 
• 84102-77-2 methyl 5-cyanobenzofuran-2-carboxylate 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 84102-75-0 5-cyanobenzo[b]furan-2-carboxylic acid 
• 501-53-1 benzyl chloroformate 
• 778553-35-8 5-amidino-2-benzofurancarboxylic acid 

Downstream Products

• 174773-83-2 ethyl trans-3-[4-[5-(benzyloxycarbonylamidino)benzofuran-2-carboxamido]cyclohexyl]propionate 
• 259150-16-8 di-tert-butyl trans-[4-(5-amidinobenzofuran-2-carboxamido)cyclohexylamino]diacetate 
• 174774-25-5 tert-butyl trans-[4-(5-amidinobenzofuran-2-carboxamido)cyclohexyl-N-(tert-butoxycarbonyl)amino]acetate 
• 174774-29-9 tert-butyl trans-[4-(5-amidinobenzofuran-2-carboxamido)cyclohexyl-N-n-butylamino]acetate 
• 789467-79-4 3-{4-[(5-carbamimidoyl-benzofuran-2-carbonyl)-amino]-cyclohexyl}-propionic acid ethyl ester 
• 174774-07-3 {4-[(5-carbamimidoyl-benzofuran-2-carbonyl)-amino]-cyclohexyloxy}-acetic acid tert-butyl ester 
• 174774-09-5 trans-[4-(5-amidinobenzofuran-2-carboxamido)cyclohexyloxy]acetic acid 
• 174774-32-4 di-tert-butyl trans-[4-[5-(benzyloxycarbonylamidino)benzofuran-2-carboxamido]cyclohexylamino]diacetate 
• 174775-08-7 [(4-{[5-(benzyloxycarbonylamino-imino-methyl)-benzofuran-2-carbonyl]-amino}-cyclohexyl)-tert-butoxycarbonyl-amino]-acetic acid tert-butyl ester 
• 174775-39-4 [(4-{[5-(benzyloxycarbonylamino-imino-methyl)-benzofuran-2-carbonyl]-amino}-cyclohexyl)-butyl-amino]-acetic acid tert-butyl ester 
• 174774-00-6 tert-butyl trans-[4-[5-(benzyloxycarbonylamidino)benzofuran-2-carboxamido]cyclohexyloxy]acetate 
• 174774-17-5 ethyl 3-[4-[(5-benzyloxycarbonylamidino)benzofuran-2-carboxamido]piperidino]propionate 

Relevant articles and documents

Preparation and pharmacological evaluation of novel glycoprotein (Gp) IIb/IIIa antagonists. 2. Condensed heterocyclic derivatives

A novel series of platelet receptor glycoprotein (Gp) IIb/IIIa antagonists with condensed heterocycles as their basic core was synthesized. In an in vitro assay, trans-4-(5-amidinobenzofuran-2- carboxamido)cyclohexyl]oxyacetic acid 17e and trans-3-[4-(5-

Fibrinogen receptor (GPIIb-IIIa) antagonists derived from 5,6-bicyclic templates. Amidinoindoles, amidinoindazoles, and amidinobenzofurans containing the N-α-sulfonamide carboxylic acid function as potent platelet aggregation inhibitors

A series of highly potent and specific fibrinogen receptor antagonists have been discovered and optimized through structural modification of the novel amidinoindole and benzofuran compounds, I and II. Systematic linker optimization afforded the amidinoben