174844-93-0Relevant articles and documents
Preparation method of aromatic vinyl bromide derivative
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Paragraph 0058-0062, (2020/09/30)
The invention discloses a preparation method of an aromatic vinyl bromide derivative, and relates to a preparation method of an aromatic vinyl bromide derivative. The invention aims to solve the problems of harsh reaction conditions, poor substrate compatibility and environmental pollution in an existing method for synthesizing aromatic vinyl bromide derivatives. The method comprises the followingsteps: dissolving an alkyne derivative, a brominated aromatic ring compound and a catalyst in an organic solvent at the room temperature in a nitrogen atmosphere, carrying out an illumination reaction, carrying out rotary evaporation on the solvent after the reaction is finished, and purifying to obtain the product. The method solves the problems of low yield, poor environmentally friendly property and poor substrate compatibility caused by the fact that existing aromatic vinyl bromide derivative synthesis needs toxic and harmful substance excitation and a transition metal catalytic system, and is applied to the field of organic synthesis.
