174913-19-0

Basic information

• Product Name: 1-bromo-2,3-dichloro-5-methoxybenzene
• Synonyms: 1-bromo-2,3-dichloro-5-methoxybenzene
• CAS NO: 174913-19-0
• Molecular Weight: 255.926
• Mol File: 174913-19-0.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 1-bromo-2,3-dichloro-5-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2,3-dichloro-5-methoxybenzene(174913-19-0)
• EPA Substance Registry System: 1-bromo-2,3-dichloro-5-methoxybenzene(174913-19-0)

Safety Data

• Hazardous Substances Data: 174913-19-0(Hazardous Substances Data)

Usage

Physical State

Colorless liquid

Odor

Faint, sweet

Primary Use

Research and chemical synthesis

Molecular Structure

A derivative of benzene with bromine, chlorine, and methoxy groups attached to the benzene ring

Industry Applications

Pharmaceutical and agrochemical industries

Purpose

Intermediate for the synthesis of various biologically active compounds

Chemical Properties

Versatile building block for the development of new drugs and agrochemicals

Safety Precaution

Handle with caution due to potential hazards and toxicity

Upstream product

• 2398-37-0 3-methoxyphenyl bromide 
• 33863-76-2 1-bromo-3-chloro-5-fluorobenzene 
• 1000577-58-1 1-bromo-2,3-dichloro-5-fluorobenzene 
• 124-41-4 sodium methylate 
• 67-56-1 methanol 
• 174913-12-3 1-bromo-3-chloro-5-methoxybenzene 

Relevant articles and documents

NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS

Provided is a compound of formula I, their synthesis and their use for treating a SHP2 mediated disorder. More particularly, provided is a pharmaceutical composition comprising the said compound.

1-(TRIAZIN-3-YL/PYRIDAZIN-3-YL)-PIPER(-AZINE)IDINE DERIVATIVES AND COMPOSITIONS THEREFOR FOR INHIBITING THE ACTIVITY OF SHP2

The present invention relates to compounds of formula I: in which Y1, Y2, Y3, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

MTH1 INHIBITORS FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE CONDITIONS

A compound of formula (I), or a pharmaceutically acceptable salt thereof, for use in the treatment of autoimmune diseases and inflammatory conditions.