17494-28-9

Basic information

• Product Name: 4-(4-BROMOBENZYL)THIOMORPHOLINE
• Synonyms: 4-(4-BROMOBENZYL)THIOMORPHOLINE;4-[(4-bromophenyl)methyl]thiomorpholine
• CAS NO: 17494-28-9
• Molecular Formula: C₁₁H₁₄BrNS
• Molecular Weight: 272.2
• Mol File: 17494-28-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-BROMOBENZYL)THIOMORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-BROMOBENZYL)THIOMORPHOLINE(17494-28-9)
• EPA Substance Registry System: 4-(4-BROMOBENZYL)THIOMORPHOLINE(17494-28-9)

Safety Data

• Hazardous Substances Data: 17494-28-9(Hazardous Substances Data)

Upstream product

• 123-90-0 Thiomorpholin 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 873-75-6 4-bromobenzenemethanol 

Downstream Products

• 1200131-28-7 4-(4-bromobenzyl)thiomorpholine 1-oxide 

Relevant articles and documents

Direct: N -alkylation of sulfur-containing amines

An efficient ruthenium-catalyzed method has been developed for the direct N-alkylation of sulfur-containing amines with alcohols, for the first time, by a step-economical and environmentally friendly hydrogen borrowing strategy. The present methodology features base-free conditions and broad substrate scope, with water being the only by-product. Moreover, this protocol has been applied to the synthesis of the pharmaceutical drug Quetiapine.

DIAZACARBAZOLES AND METHODS OF USE

The invention relates to 1,7-diazacarbazole compounds of Formula (I), (I-a) and (I-b) which are useful as kinase inhibitors, more specifically useful as checkpoint kinase 1 (chkl) inhibitors, thus useful as cancer therapeutics. The invention also relates to compositions, more specifically pharmaceutical compositions comprising these compounds and methods of using the same to treat various forms of cancer and hyperproliferative disorders, as well as methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.