174953-28-7

Basic information

• Product Name: (1S,2R)-1,2-epoxy-1-phenylbutane
• Synonyms: (1S,2R)-1,2-epoxy-1-phenylbutane
• CAS NO: 174953-28-7
• Molecular Weight: 148.205
• Mol File: 174953-28-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1S,2R)-1,2-epoxy-1-phenylbutane(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-1,2-epoxy-1-phenylbutane(174953-28-7)
• EPA Substance Registry System: (1S,2R)-1,2-epoxy-1-phenylbutane(174953-28-7)

Safety Data

• Hazardous Substances Data: 174953-28-7(Hazardous Substances Data)

Upstream product

• 73951-64-1 cis-2-ethyl-3-phenyl-oxirane 
• 1560-09-4 (Z)-but-1-en-1-ylbenzene 
• 824-90-8 1-phenylbut-1-ene 

Relevant articles and documents

Novel chiral (salen)MnIII complexes containing a calix[4]arene unit as catalysts for enantioselective epoxidation reactions of (Z)-aryl alkenes

New asymmetric (salen)MnIII and UO2 complexes containing a calix[4]arene unit in the ligand framework were synthesized. The UO2 complexes were characterized by 1H-, 13C-, 2D TOCSY and T-ROESY NMR spectroscopy. Furthermore, the structure of one UO 2 complex was determined by single-crystal X-ray analysis. The data showed that UO2 complexes, which can be considered in first approximation models of the Mn=O oxidant active species, possess a chiral pocket and adopt relevant conformations for the selectivity of the oxygen transfer process. Epoxidation data of model alkenes with the MnIII complexes showed moderate ee values and were not conclusive in indicating that the calix[4]arene unit might be able to influence the selectivity by a molecular recognition mechanism. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.

Enantioconvergent transformation of racemic cis-β-alkyl substituted styrene oxides to (R,R) threo diols by microsomal epoxide hydrolase catalysed hydrolysis

Both enantiomers of cis-β-ethyl, β-n-propyl, β-n-butyl, and β-n-hexyl substituted styrene oxides undergo microsomal epoxide hydrolase catalysed hydration at the (S) carbon to give the corresponding (R, R) threo diols in a > 90% e.e. A complete kinetic resolution of the racemic epoxide is also obtained with the β-ethyl substituted substrate, but not with its higher homologues.