175075-24-8 Usage
Description
5-Aminosulfonyl-2-Ox-Indole, also known as 2,3-Dihydro-2-oxo-1H-indole-5-sulfonamide (CAS# 175075-24-8), is an organic compound with a light-brown solid appearance. It is characterized by its unique chemical structure, which includes an indole ring with a sulfonamide group at the 5-position and an oxo group at the 2-position. 5-Aminosulfonyl-2-Ox-Indole is known for its utility in various organic synthesis processes.
Uses
Used in Organic Synthesis:
5-Aminosulfonyl-2-Ox-Indole is used as a synthetic intermediate for the development of various organic compounds. Its unique structure allows it to be a versatile building block in the synthesis of a wide range of molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-Aminosulfonyl-2-Ox-Indole is used as a key component in the synthesis of novel drug candidates. Its incorporation into drug molecules can potentially enhance their pharmacological properties, such as potency, selectivity, and bioavailability.
Used in Agrochemical Industry:
5-Aminosulfonyl-2-Ox-Indole is also utilized in the agrochemical industry for the development of new pesticides and other crop protection agents. Its unique chemical structure can be exploited to create molecules with improved activity against pests and diseases, as well as enhanced safety and environmental profiles.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 5-Aminosulfonyl-2-Ox-Indole can be used as a starting material for the synthesis of various dyes and pigments. Its light-brown solid appearance suggests that it may contribute to the color properties of the final products, potentially leading to the development of new colorants with unique characteristics.
Used in Research and Development:
5-Aminosulfonyl-2-Ox-Indole is also valuable in research and development settings, where it can be used to explore new reaction pathways, study the effects of structural modifications on molecular properties, and develop new synthetic methodologies. Its use in research can contribute to the advancement of chemical science and the discovery of innovative applications across various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 175075-24-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,0,7 and 5 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 175075-24:
(8*1)+(7*7)+(6*5)+(5*0)+(4*7)+(3*5)+(2*2)+(1*4)=138
138 % 10 = 8
So 175075-24-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2O3S/c9-14(12,13)6-1-2-7-5(3-6)4-8(11)10-7/h1-3H,4H2,(H,10,11)(H2,9,12,13)
175075-24-8Relevant articles and documents
FORMULATIONS FOR PHARMACEUTICAL AGENTS IONIZABLE AS FREE ACIDS OR FREE BASES
-
Page/Page column 170; 220, (2008/06/13)
-
5-sulfonamido-substituted indolinone compounds as protein kinase inhibitors
-
Page/Page column 28, (2010/02/08)
The present invention relates to 5-sulfonamido substituted indolinones that modulate the activity of protein kinases (“PKs”). The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
Design and synthesis of aminopropyl tetrahydroindole-based indolin-2-ones as selective and potent inhibitors of Src and Yes tyrosine kinase
Guan, Huiping,Laird, A. Douglas,Blake, Robert A.,Tang, Cho,Liang, Chris
, p. 187 - 190 (2007/10/03)
A novel series of substituted 3-[3-(aminopropyl)-4,5,6,7-tetrahydro-1H- indol-2-ylmethylene]-1,3-dihydro-indole-2-ones was discovered as potent inhibitors of the non-receptor tyrosine kinase Src and Yes. A structure-activity relationship was developed in order to optimize their potency and selectivity. Syntheses of these compounds are also described herein.
