175090-71-8

Basic information

• Product Name: N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methoxybenzamide
• Synonyms: N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methoxybenzamide
• CAS NO: 175090-71-8
• Molecular Weight: 341.751
• Mol File: 175090-71-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methoxybenzamide(175090-71-8)
• EPA Substance Registry System: N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methoxybenzamide(175090-71-8)

Safety Data

• Hazardous Substances Data: 175090-71-8(Hazardous Substances Data)

Upstream product

• 2797-51-5 quinoclamine 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 175090-52-5 N-(3-Ethylamino-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-4-methoxy-benzamide 

Relevant articles and documents

Synthesis and antiplatelet, antiinflammatory, and antiallergic activities of 2-substituted 3-chloro-1,4-naphthoquinone derivatives

A series of 2-substituted 3-chloro-1,4-naphthoquinones was synthesized, and the antiplatelet, antiinflammatory, and antiallergic activities of these compounds were evaluated. The structure-activity relationships in this series were also examined. Most of the 2-alkyl/arylcarboxamido derivatives of 3-chloro-1,4-naphthoquinone showed potent activities with similar trends in each of the activities evaluated.

COMPOUNDS AND PHARMACEUTICAL COMPOSITION ASSOCIATED WITH UBIQUITINATION-PROTEASOME SYSTEM

The invention relates to new compounds with low cytotoxicity for blocking ubiquitination- proteasome system in diseases. Accordingly, these compounds can be used in treatment of treating disorders including, but not limited to, cancers, neurodegenerative